TY - GEN
T1 - One-Pot Synthesis of 2-Phenylquinoline-4-Carboxylic Acid
T2 - 5th International Conference on Materials Sciences and Nanomaterials, ICMSN 2021 and 4th International Conference on Advanced Composite Materials, ICACM 2021
AU - Halim, Ayu Mutmainnah
AU - Cahyana, Antonius Herry
AU - Yunarti, Rika Tri
N1 - Funding Information:
The authors would like to thank Indonesia Endowment Fund for Education (Lembaga Pengelola Dana pendidikan, LPDP) for providing the full scholarship of the first author and research grant to support this study.
Publisher Copyright:
© 2022 Trans Tech Publications Ltd, Switzerland.
PY - 2022
Y1 - 2022
N2 - Iron(III) trifluoromethanesulfonate [Fe(OTF)3] has been proven to be an effective catalyst in the synthesis of 2-phenylquinoline-4-carboxylic acid by the Doebner reaction using one-pot pyruvic acid, aniline, and benzaldehyde. This method shows attractive characteristics including concise one-pot conditions, high atom economy, very limited energy consumption, and the sequential catalytic process requires only a catalytic (15 mol%) amount of Fe(OTf)3 with short reaction periods (3 h) . Meanwhile, the catalyst was easily recovered from the reaction system and reused smoothly with only a little loss of activity.
AB - Iron(III) trifluoromethanesulfonate [Fe(OTF)3] has been proven to be an effective catalyst in the synthesis of 2-phenylquinoline-4-carboxylic acid by the Doebner reaction using one-pot pyruvic acid, aniline, and benzaldehyde. This method shows attractive characteristics including concise one-pot conditions, high atom economy, very limited energy consumption, and the sequential catalytic process requires only a catalytic (15 mol%) amount of Fe(OTf)3 with short reaction periods (3 h) . Meanwhile, the catalyst was easily recovered from the reaction system and reused smoothly with only a little loss of activity.
KW - 2-phenylquinoline-4-carboxylic acid
KW - Doebner reaction
KW - Iron(III) trifluoromethanesulfonate
KW - one-pot reaction
UR - http://www.scopus.com/inward/record.url?scp=85127226961&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.907.97
DO - 10.4028/www.scientific.net/KEM.907.97
M3 - Conference contribution
AN - SCOPUS:85127226961
SN - 9783035718942
T3 - Key Engineering Materials
SP - 97
EP - 102
BT - Advanced Materials Science and Technologies II - Selected peer-reviewed full text papers from 5th International Conference on Materials Sciences and Nanomaterials, ICMSN 2021 and 4th International Conference on Advanced Composite Materials, ICACM 2021
A2 - Zhao, Yuyuan
PB - Trans Tech Publications Ltd
Y2 - 25 August 2021 through 27 August 2021
ER -
