Phenazine is one of the most important organic compounds because of its various biological activities. This study aims to synthesize the phenazine derivatives compound using 2-hydroxy-1,4-naphthoquinone (lawsone) with a one-pot four-component method.Phenazine derivative that had been successfully synthesized was carried out by reacting four reactants at once in one flask with the same mole ratio. The reaction occurred between lawsone, o-phenylenediamine, benzaldehyde, and malononitrile. Characterization of the synthesized products was confirmed using FT-IR, UV-Vis Spectrophotometer, and LC-MS. The results of the analysis using several of these instruments obtained one compound, namely 3-amino-2-cyano-1-phenyl-1H-benzo[a]pyrano[2,3-c]phenazine. The reaction conditions were carried out at 50 C for 6 h in ethanol with unassisted catalysts and obtained a product yield of 45%.
|Journal||IOP Conference Series: Materials Science and Engineering|
|Publication status||Published - 2020|
|Event||4th International Symposium on Current Progress in Functional Materials, ISCPFM 2019 - Bali, Indonesia|
Duration: 6 Nov 2019 → 7 Nov 2019