Neuroophthalmic manifestation of cortical brain tumor in Dr. Cipto Mangunkusumo General Hospital Indonesia

Novita ayu Sinthia, Tiara Aninditha, Ni nengah rida Ariarini, Freddy Sitorus, Darma Imran, Pukovisa Prawiroharjo, Henry riyanto Sofyan, Ramdinal aviesena Zairinal, Dinda Diafiri

Research output: Contribution to conferencePaperpeer-review


Brain tumor is a disease that can cause focal and global neurological deficit, one of them is neuroophthalmic (NO) manifestation. Visual system has contact with all brain areas which can be destroyed by presence of brain tumor. In Indonesia, diagnostic tools are limited so neuroophthalmic clinical ability is very important to detect brain tumor symptoms as early as possible. Some brain areas are characterized by well-known NO manifestations, such as specific bitemporal hemianopsia in sellar region tumor and eye movement disorder in brainstem tumor. Frontal lobe (cortex area) is the most common location of brain tumor, but very few studies have specifically investigated NO manifestations of cortical brain tumor. Such data was not available in Indonesia, then this study was conducted.

Study design was cross-sectional observational study to determine pattern of tumor characteristics and NO manifestations of cortical brain tumor. The study subjects were patients undergoing preoperative NO examinations in January 2014 December 2019 and had brain tumor histology results. Tumors with multiple location overlapping sellar or infratentorial region were excluded. Categorical data was presented in frequency/percentage.

From 70 brain tumor subjects who had histology results, there were 20 subjects (28.6%) of pure cortical brain tumor predominantly primary brain tumor (60%). Among those, meningiomas and astrocytomas are the most common tumor type (25% each). Lung was the most common source of metastatic brain tumors (15%). Most tumors have more than one location (70%) predominantly unilateral distribution. All subjects in this study had NO manifestations. The most common NO abnormalities was fundoscopic abnormalities (90%) mostly papilledema (67.7%). The second common is visual impairment (70%). Meanwhile, eye movement disorders and visual field disturbances occupy only 35% and 15% portion
Original languageEnglish
Publication statusPublished - 2022
EventWFNOS 2022 Seoul - Korea
Duration: 24 Mar 202227 Mar 2022


ConferenceWFNOS 2022 Seoul


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