Mycobacterium tuberculosis Beijing genotype strains associated with febrile response to treatment

Reinout Van Crevel, Ron H.H. Nelwan, Wilma De Lenne, Yelilsan Veeraragu, Adri G. Van Der Zanden, Zulkifli Amin, Jos W.M. Van Der Meer, Dick Van Soolingen

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99 Citations (Scopus)

Abstract

DNA fingerprinting has demonstrated predominance of the Beijing genotype among Mycobacterium tuberculosis strains isolated in Southeast Asia. We prospectively examined the occurrence of Beijing genotype strains in tuberculosis patients in Indonesia. Early in treatment, patients infected with Beijing genotype strains more often had fever unrelated to disease severity, toxicity, or drug resistance, indicating that Beijing genotype strains may have specific pathogenic properties.

Original languageEnglish
Pages (from-to)880-883
Number of pages4
JournalEmerging Infectious Diseases
Volume7
Issue number5
DOIs
Publication statusPublished - 1 Jan 2001

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    Van Crevel, R., Nelwan, R. H. H., De Lenne, W., Veeraragu, Y., Van Der Zanden, A. G., Amin, Z., Van Der Meer, J. W. M., & Van Soolingen, D. (2001). Mycobacterium tuberculosis Beijing genotype strains associated with febrile response to treatment. Emerging Infectious Diseases, 7(5), 880-883. https://doi.org/10.3201/eid0705.017518