Abstract
Medulloblastoma is the most common malignant brain tumor in pediatric patients. Leptomeningeal dissemination often occurs in the spinal canal and rarely into the supratentorial as an extra-axial lesion. This study followed an 8-year progression of multifocal medulloblastoma recurrence as supratentorial metastasis that mimics an intra-axial mass of the temporal lobe. Pathologic examination of the temporal mass showed densely packed small round blue cells that are distributed in a ribboning pattern with areas of necrosis, rosette formation, and mitosis. Ki-67 immunohistochemical staining of the tumor showed a high proliferation index of 40% and revealed positive results for synaptophysin and negative results for glial fibrillary acidic protein and Β-catenin. A long follow-up is essential to diagnose the recurrence and elucidate the progression of medulloblastoma.
Original language | English |
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Pages (from-to) | 93-99 |
Number of pages | 7 |
Journal | Medical Journal of Indonesia |
Volume | 29 |
Issue number | 1 |
DOIs | |
Publication status | Published - Mar 2020 |
Keywords
- Intra-axial mass
- Long follow-up
- Medulloblastoma
- Recurrence