TY - JOUR
T1 - Multidrug-Resistant Organisms Infection on Mortality of Burn Patients at Public Hospital X in Jakarta
T2 - A Retrospective Study
AU - Veronica, Raja Merlinda
AU - Kumalawati, July
AU - Rumende, Cleopas Martin
AU - Nainggolan, Leonard
AU - Simadibrata, Marcellus
AU - Shatri, Hamzah
AU - Yunir, Em
AU - Wardhana, Aditya
AU - Nelwan, Erni Juwita
AU - Rustam, Musfardi
N1 - Publisher Copyright:
Copyright @ 2024, Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
PY - 2024/7
Y1 - 2024/7
N2 - Susceptibility to infection and increasing antibiotic resistance put burn patients at risk of developing infections caused by multidrug-resistant organisms (MDRO). This condition can progress to sepsis, increasing morbidity and mortality. This retrospective cohort study employed the medical record data of patients treated at Public Hospital X in Jakarta, Indonesia, from January 2020 to June 2022. Of 160 subjects, most were aged <60 years (82.5%) and had comorbidities (16.88%). The most common cause of burns was fire (86.25%). The use of medical devices was 90.63%, with a 14-day median length of stay. The most common gram-negative MDRO pathogens were K. pneumoniae (29.91%), Enterobacter sp (22.32%), and Acinetobacter (20.54%); 45% of patients infected with MDRO died. The bivariate analysis found an increased risk of death due to MDRO infection in burn patients (RR 1.103; 95%CI 1.004-1.211, p-value = 0.046). After adjusting for role variables (age, comorbidities, total body surface area, use of medical devices, length of stay) and from multivariate analysis, the confounding variables for MDRO infection and mortality were length of stay and age. MDRO infection increases the mortality rate in burn patients. Mortality in burn patients due to MDRO infection is greater than non-MDRO.
AB - Susceptibility to infection and increasing antibiotic resistance put burn patients at risk of developing infections caused by multidrug-resistant organisms (MDRO). This condition can progress to sepsis, increasing morbidity and mortality. This retrospective cohort study employed the medical record data of patients treated at Public Hospital X in Jakarta, Indonesia, from January 2020 to June 2022. Of 160 subjects, most were aged <60 years (82.5%) and had comorbidities (16.88%). The most common cause of burns was fire (86.25%). The use of medical devices was 90.63%, with a 14-day median length of stay. The most common gram-negative MDRO pathogens were K. pneumoniae (29.91%), Enterobacter sp (22.32%), and Acinetobacter (20.54%); 45% of patients infected with MDRO died. The bivariate analysis found an increased risk of death due to MDRO infection in burn patients (RR 1.103; 95%CI 1.004-1.211, p-value = 0.046). After adjusting for role variables (age, comorbidities, total body surface area, use of medical devices, length of stay) and from multivariate analysis, the confounding variables for MDRO infection and mortality were length of stay and age. MDRO infection increases the mortality rate in burn patients. Mortality in burn patients due to MDRO infection is greater than non-MDRO.
KW - burn
KW - mortality
KW - multidrug-resistant organisms
UR - http://www.scopus.com/inward/record.url?scp=85201095849&partnerID=8YFLogxK
U2 - 10.21109/kesmas.v19isp1.1761
DO - 10.21109/kesmas.v19isp1.1761
M3 - Article
AN - SCOPUS:85201095849
SN - 1907-7505
VL - 19
SP - 76
EP - 83
JO - Kesmas: Jurnal Kesehatan Masyarakat Nasional
JF - Kesmas: Jurnal Kesehatan Masyarakat Nasional
IS - 5
ER -
