Multibasillary leprae borderline lepromatous type with erythema nodosum leprosum reaction: Establishing the diagnosis

Achmad Satya Negara, Harijono Kariosentono, Wibisono Nugraha, Budi Eko Prasetyorini, Ferry Arrochman, Ria Margiana

Research output: Contribution to journalArticlepeer-review

Abstract

Leprosy is a chronic infectious disease with major involvement in the skin and peripheral nervous system caused by the bacterium bacillus Mycobacterium leprae. Borderline lepromatous (BL) is one of leprosy types characterized by annular with poorly demarcated outer borders and sharply defined punch out centers. This case report aimed to know and establish the diagnosis of multibasillary leprae borderline lepromatous. A 65 year old man came with a complaint of numbed erythematous patches. Smear test showed the presence of IB + 3 and IM 10%. Histopathological examination found red intact acid bacilli. Based on these findings we diagnosed him with multibasillary borderline lepromatous. We gave multy drugs therapy (MDT) for MB type for 12 months. But at 4 month follow up ENL reaction appeared thus. We managed him with continued MDT and prednisone 40 mg / 24 hours with tappered dose the ENL clinical improvement. The clinical feature of leprosy depends on the host response. Skin lesions can be hypoesthesia or anesthesia. The peripheral nerve is palpable and thick. Symmetrical anesthesia of the fingertips may also occur.

Original languageEnglish
Pages (from-to)5921-5925
Number of pages5
JournalAnnals of the Romanian Society for Cell Biology
Volume25
Issue number1
Publication statusPublished - 2021

Keywords

  • Borderline lepromatous
  • Erythema nodusum leprosum
  • Leprosy

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