Keyphrases
Doxorubicin-induced Cardiotoxicity
100%
Mitochondrial Biogenesis
100%
Modulatory Activity
100%
Moringa Oleifera Leaf Extract
100%
MRNA Expression
80%
Doxorubicin
80%
8-hydroxydeoxyguanosine (8-OHdG)
60%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
60%
Activating Receptors
60%
Coactivator
60%
Peroxisome
60%
Glutathione Peroxidase (GSH-Px)
40%
Caspase-3
40%
Mitochondrial DNA Copy number
40%
Once-weekly
40%
Superoxide Dismutase 2 (SOD2)
40%
Possible Causes
20%
Oxidative Stress
20%
Sprague-Dawley Rats
20%
Gene Expression
20%
Antioxidant System
20%
Antioxidant Properties
20%
Anticancer
20%
Apoptosis
20%
Cardiotoxicity
20%
Cardiac Damage
20%
Anthracyclines
20%
Cardioprotection
20%
Creatine kinase-MB (CK-MB)
20%
Malondialdehyde Level
20%
Aqueous Leaf Extract
20%
Cardiomyocyte Apoptosis
20%
Malondialdehyde
20%
Cardiac Tissue
20%
Moringa Oleifera Leaves
20%
Moringa Oleifera
20%
Serious Adverse Effects
20%
Mitochondrial Dysfunction
20%
Blood Tissue
20%
Cardiac Biomarkers
20%
Protein Synthesis Inhibition
20%
Biogenesis Pathway
20%
Nucleic Acid Synthesis
20%
Naturally-derived
20%
INIS
mitochondria
100%
rats
100%
doxorubicin
100%
messenger-rna
57%
receptors
42%
levels
42%
superoxide dismutase
28%
apoptosis
28%
dna
28%
biological markers
28%
glutathione
28%
peroxidases
28%
oxidation
14%
reduction
14%
proteins
14%
medicine
14%
tissues
14%
synthesis
14%
blood
14%
damage
14%
elevation
14%
genes
14%
inhibition
14%
nucleic acids
14%
Pharmacology, Toxicology and Pharmaceutical Science
Cardiotoxicity
100%
Doxorubicin
100%
Moringa oleifera
100%
Transcription Factor Nrf2
57%
Messenger RNA
57%
Receptor
42%
Biological Marker
28%
Malonaldehyde
28%
Glutathione Peroxidase
28%
Caspase 3
28%
Manganese Superoxide Dismutase
28%
Mitochondrial DNA
28%
Antioxidant
14%
Antiinfective Agent
14%
Sprague Dawley Rat
14%
Anthracycline
14%
Heart Injury
14%
Peroxidase
14%
8 Hydroxydeoxyguanosine
14%
Lactate Dehydrogenase
14%
Nucleic Acid
14%
Biochemistry, Genetics and Molecular Biology
Mitochondrial Disorder
14%