Monoclonal antibodies to human IgM

Agus Sjahrurachman, Agustin Indrawaii, Beti Ernawati Dewi, R. Fera Ibrahim, Mardiastuti

Research output: Contribution to journalArticlepeer-review


Availability of specific antihuman IgM antibodies is very important for developing diagnostic kits for infectious diseases that are highly prevalent in Indonesia. In line with such idea, an attempt to construct hybridoma cells producing antihuman IgM antibodies is done by fusing NS-1 myeloma cell line with immunized mouse spleen cells. Hybridomas producing anti human IgM antibodies have been obtained and antibodies produced by several exhaustedly cloned hybridomas has been characterized. Those antibodies are not reactive to human IgG, IgA nor IgG and IgA-deprived human serum and belong to IgG2a subclass.

Original languageEnglish
Pages (from-to)218-221
Number of pages4
JournalMedical Journal of Indonesia
Issue number4
Publication statusPublished - 1 Oct 1999


  • Antihuman IgM
  • Diagnostic
  • Monoclonal antibody
  • Mouse hybridoma


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