Monitoring of anticonvulsant drug side effects in outpatients with epilepsy

Santi Purna Sari; S. Natasha Kurnia Salma; Alfina Rianti

doi:10.22159/ijap.2018.v10s1.67

Monitoring of anticonvulsant drug side effects in outpatients with epilepsy

Santi Purna Sari, S. Natasha Kurnia Salma, Alfina Rianti

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: This study aimed to monitor the side effects of carbamazepine, phenytoin, and valproic acid, and combinations of these drugs in adult patients with epilepsy, to raise awareness of the importance of drug side effect monitoring in hospitals. Methods: In this prospective study, descriptive data were collected from patients who met the inclusion criteria of complete samples. Primary data were obtained using questionnaires, secondary data were collected from medical records, and analyses were performed using the Naranjo algorithm. Results: Among the 54 included patients, 38 (70.37%) of them experienced drug side effects, and the most frequently observed side effect occurred in 48.15% of study subjects. Conclusion: No correlation was identified between side effects and age (p=0.903) or gender (p=1.000).

Original language	English
Pages (from-to)	303-306
Number of pages	4
Journal	International Journal of Applied Pharmaceutics
Volume	10
Issue number	Special Issue 1
DOIs	https://doi.org/10.22159/ijap.2018.v10s1.67
Publication status	Published - 1 Dec 2018

Keywords

Carbamazepine
Naranjo algorithm
Phenytoin
Side effects
Valproic acid

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10.22159/ijap.2018.v10s1.67

Cite this

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title = "Monitoring of anticonvulsant drug side effects in outpatients with epilepsy",

abstract = "Objective: This study aimed to monitor the side effects of carbamazepine, phenytoin, and valproic acid, and combinations of these drugs in adult patients with epilepsy, to raise awareness of the importance of drug side effect monitoring in hospitals. Methods: In this prospective study, descriptive data were collected from patients who met the inclusion criteria of complete samples. Primary data were obtained using questionnaires, secondary data were collected from medical records, and analyses were performed using the Naranjo algorithm. Results: Among the 54 included patients, 38 (70.37%) of them experienced drug side effects, and the most frequently observed side effect occurred in 48.15% of study subjects. Conclusion: No correlation was identified between side effects and age (p=0.903) or gender (p=1.000).",

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Monitoring of anticonvulsant drug side effects in outpatients with epilepsy

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Keywords

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