@inproceedings{2e4451b4bed94cc2a8199ffe3d0fcd23,
title = "Modification of nitrogen-terminated boron-doped diamond electrodes with gold nanoparticles and hemoglobin for acrylamide biosensors",
abstract = "Boron-doped diamond (BDD) was modified with gold nanoparticles (AuNPs) and hemoglobin (Hb) through nitrogen groups on the surface of BDD to produce an electrode with good selectivity, sensitivity, and affinity to be applied as an acrylamide biosensor. Prior to modification with Hb, the BDD was modified with AuNPs to increase the affinity of BDD with nitrogen termination (N-BDD) towards Hb. The electrochemical behavior of the hemoglobin-modified with gold nanoparticles on the surface of N-BDD electrode (Hb-AuNPs-N-BDD) in the presence of acrylamide was studied in comparison to hemoglobin-modified gold electrodes (Hb-Au). Cyclic voltammetry indicated the optimum concentration of Hb was obtained at 0.6 mg/mL in Hb-Au electrode and 0.02 mg/mL in Hb-AuNPs-N-BDD electrode. The responses were linear against the acrylamide concentration range of 0 - 30 μM with an estimated LOD of 38.15 μM at Hb-Au electrode and 13.10 μM at Hb-AuNPs-BDDN electrode. The results indicated that Hb-AuNPs-N-BDD electrode has a better performance than Hb-Au electrode as the acrylamide sensors.",
keywords = "Acrylamide, Biosensor, Boron-Doped Diamond, Gold Nanoparticles, Hemoglobin",
author = "Annisa, {T. N.} and E. Saepudin and Ivandini, {T. A.}",
note = "Publisher Copyright: {\textcopyright} 2018 Author(s).; 3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017 ; Conference date: 26-07-2017 Through 27-07-2017",
year = "2018",
month = oct,
day = "22",
doi = "10.1063/1.5064105",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Ratna Yuniati and Terry Mart and Anggraningrum, {Ivandini T.} and Djoko Triyono and Sugeng, {Kiki A.}",
booktitle = "Proceedings of the 3rd International Symposium on Current Progress in Mathematics and Sciences 2017, ISCPMS 2017",
address = "United States",
}