Modification of boron-doped diamond with gold through wet-chemical seeding and electrodeposition techniques for the application of acrylamide biosensor

L. E. Anggraini, E. Saepudin, T. A. Ivandini

Research output: Contribution to journalConference articlepeer-review

Abstract

Acrylamide is known as carcinogenic and neurotoxin substrates. An alternative method for acrylamide detection is by using hemoglobin-based biosensors as it can provide a simple, rapid, and sensitive method. In this research, the electrodes for biosensor of acrylamide were prepared by modifying boron-doped diamond (BDD) with gold and hemoglobin (Hb). Wet-chemical seeding followed by electrochemical overgrowth of seeds technique was performed to modify the BDD electrodes with gold. The characterization with Scanning Electron Microscopy-Energy Dispersive Spectroscopy X-Ray (SEM-EDS) showed the gold coverage of 12.74 % on the BDD surface. The gold-modified BDD was then modified with 0.25 mM Hb. The prepared sensor can be successfully applied in the concentration range of acrylamide from 0.6 to 6 μM with high linearity (R2 = 0.9901) and an estimated limit of detection of 0.845 μM.

Original languageEnglish
Article number012019
JournalIOP Conference Series: Materials Science and Engineering
Volume763
Issue number1
DOIs
Publication statusPublished - 28 Apr 2020
Event3rd International Symposium on Current Progress in Functional Materials 2018, ISCPFM 2018 - Depok, Indonesia
Duration: 8 Aug 20189 Aug 2018

Keywords

  • acrylamide
  • biosensor
  • boron-doped diamond
  • gold
  • hemoglobin

Fingerprint Dive into the research topics of 'Modification of boron-doped diamond with gold through wet-chemical seeding and electrodeposition techniques for the application of acrylamide biosensor'. Together they form a unique fingerprint.

Cite this