TY - JOUR
T1 - Microfluidic platform for environmental contaminants sensing and degradation based on boron-doped diamond electrodes
AU - Medina-Sánchez, Mariana
AU - Mayorga-Martinez, Carmen C.
AU - Watanabe, Takeshi
AU - Ivandini, Tribidasari A.
AU - Honda, Yuki
AU - Pino, Flavio
AU - Nakata, Azuya
AU - Fujishima, Akira
AU - Einaga, Yasuaki
AU - Merkoçi, Arben
N1 - Publisher Copyright:
© 2015 Elsevier B.V.
PY - 2016/1/15
Y1 - 2016/1/15
N2 - We have developed a lab-on-a-chip (LOC) platform for electrochemical detection and degradation of the pesticide atrazine (Atz). It is based on boron-doped diamond (BDD) electrodes and a competitive magneto-enzyme immunoassay (EIA) that enables high sensitivity. To detect the enzymatic reaction, we employed a BDD electrode modified with platinum nanoparticles (PtNPs), as a highly conductive catalytic transducer. Chronoamperometry revealed a limit of detection (LOD) of 3.5pM for atrazine, which, to the best of our knowledge, is one of the lowest value published to date. Finally, we degraded Atz in the same platform, using a bare BDD electrode that features remarkable corrosion stability, a wide potential window, and much higher O 2 overvoltage as compared to conventional electrodes. These characteristics enable the electrode to produce a greater amount of HO • on the anode surface than do conventional electrodes and consequently, to destroy the pollutant more rapidly. Our new LOC platform might prove interesting as a smart system for detection and remediation of diverse pesticides and other contaminants.
AB - We have developed a lab-on-a-chip (LOC) platform for electrochemical detection and degradation of the pesticide atrazine (Atz). It is based on boron-doped diamond (BDD) electrodes and a competitive magneto-enzyme immunoassay (EIA) that enables high sensitivity. To detect the enzymatic reaction, we employed a BDD electrode modified with platinum nanoparticles (PtNPs), as a highly conductive catalytic transducer. Chronoamperometry revealed a limit of detection (LOD) of 3.5pM for atrazine, which, to the best of our knowledge, is one of the lowest value published to date. Finally, we degraded Atz in the same platform, using a bare BDD electrode that features remarkable corrosion stability, a wide potential window, and much higher O 2 overvoltage as compared to conventional electrodes. These characteristics enable the electrode to produce a greater amount of HO • on the anode surface than do conventional electrodes and consequently, to destroy the pollutant more rapidly. Our new LOC platform might prove interesting as a smart system for detection and remediation of diverse pesticides and other contaminants.
KW - Atrazine degradation
KW - Atrazine detection
KW - Biosensor
KW - Boron-doped diamond electrode
KW - Microfluidics
KW - Platinum nanostructured particles
UR - http://www.scopus.com/inward/record.url?scp=84940518216&partnerID=8YFLogxK
U2 - 10.1016/j.bios.2015.08.058
DO - 10.1016/j.bios.2015.08.058
M3 - Article
C2 - 26339934
AN - SCOPUS:84940518216
SN - 0956-5663
VL - 75
SP - 365
EP - 374
JO - Biosensors and Bioelectronics
JF - Biosensors and Bioelectronics
ER -