Microencapsulation of clove oil using spray dry with casein encapsulator and activity test towards Streptococcus mutans

Muhamad Sahlan, Sindy Fitriani Lestari, Teti Indrawati, Diah Kartika Pratami, Anondho Wijarnako, Heri Hermansyah, Kenny Lischer, Alif Nadhif Rabbani

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Clove oil originates from leaves, flower, and trunks of clove plant (Syzigium aromaticum) that is volatile and prone to both temperature and light. Clove oil generally uses as medicine due to properties such as analgesic, antibacterial, antioxidant, antifungal, and antivirus. This research aims to decrease the rate of clove oil evaporation by making it into a microcapsule. This research starts with the isolation of clove with a spray dryer using a casein encapsulator. Microcapsule resulted is evaluated in both physically and chemically as it is also tested for activity towards Streptococcus mutans. The result of clove oil microcapsule is in the shape of white-yellowish color crystal powder with a unique smell of clove. The particle shape is round with pores in the size of 1.16μm, encapsulation efficiency of 97.78%, loading capacity 62.24%, water content 12.59%, solubility in water 91.65%. Microcapsule activity test of clove oil shows inhibition as an antibacterial towards Streptococcus mutans of 1.663 CFU with a minimum inhibition concentration of 0.25g/mL and an inhibitory rate of 11.8±1.0 mm. Clove oil could be made into microcapsule with casein as an en which also having antibacterial activity towards Streptococcus mutans.

Original languageEnglish
Title of host publication4th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices
Subtitle of host publicationProceedings of the International Symposium of Biomedical Engineering, ISBE 2019
EditorsKenny Lischer, Tomy Abuzairi, Siti Fauziyah Rahman, Misri Gozan
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735419445
DOIs
Publication statusPublished - 10 Dec 2019
Event4th International Symposium of Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices, ISBE 2019 - Padang, West Sumatera, Indonesia
Duration: 22 Jul 201924 Jul 2019

Publication series

NameAIP Conference Proceedings
Volume2193
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference4th International Symposium of Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices, ISBE 2019
CountryIndonesia
CityPadang, West Sumatera
Period22/07/1924/07/19

Keywords

  • Casein
  • Clove Oil
  • Microcapsule
  • Spray Dryer
  • Streptococcus mutans

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