MEKANISME IMUNODEPRESI PASCASTROKE

Al Rasyid

doi:10.52386/neurona.v36i3.78

MEKANISME IMUNODEPRESI PASCASTROKE

Translated title of the contribution: POST-STROKE IMMUNODEPRESSION MECHANISMS

Al Rasyid

Department of Neurology

Research output: Contribution to journal › Article › peer-review

Abstract

Immunodepression refers to a condition when immune system has reduced capacity to fulfill its functions therefore leading to infection. Infections develop frequently after stroke, and have been associated with poor clinical and functional outcome. Several studies show ischemic stroke, leads to impairment of immune responses, which increases susceptibility of an infection. This review analyzes the mechanisms of post-stroke immunodepression involving nervous system, such as adrenergic pathway, cholinergic pathway, or HPA axis, comprehensively based on recent clinical and experimental evidences. A better understanding of immune system modification after stroke could encourage further studies regarding immunomodulation therapy use in fighting infection

Translated title of the contribution	POST-STROKE IMMUNODEPRESSION MECHANISMS
Original language	Indonesian
Pages (from-to)	217-225
Journal	6th JAKNEWS 2019 - Jakarta Neurology Exhibition Workshop and Symposium. Maret 2019
Volume	36
Issue number	3
DOIs	https://doi.org/10.52386/neurona.v36i3.78 https://doi.org/10.52386/neurona.v36i3
Publication status	Published - 1 Jun 2019

Keywords

Immune response
nfection
post-stroke immunodepression

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http://ejournal.neurona.web.id/index.php/neurona/article/view/78

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abstract = "Immunodepression refers to a condition when immune system has reduced capacity to fulfill its functions therefore leading to infection. Infections develop frequently after stroke, and have been associated with poor clinical and functional outcome. Several studies show ischemic stroke, leads to impairment of immune responses, which increases susceptibility of an infection. This review analyzes the mechanisms of post-stroke immunodepression involving nervous system, such as adrenergic pathway, cholinergic pathway, or HPA axis, comprehensively based on recent clinical and experimental evidences. A better understanding of immune system modification after stroke could encourage further studies regarding immunomodulation therapy use in fighting infection",

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MEKANISME IMUNODEPRESI PASCASTROKE

Abstract

Keywords

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