TY - JOUR
T1 - Magnetically separable Fe3O4/graphene oxide nanocomposite
T2 - An efficient heterogenous catalyst for spirooxindole derivatives synthesis
AU - Cahyana, Antonius Herry
AU - Liandi, Agus Rimus
AU - Maghdalena, Maria
AU - Yunarti, Rika Tri
AU - Wendari, Tio Putra
N1 - Funding Information:
The authors acknowledge financial support from the Universitas Indonesia through the grant of Program Publikasi Terindeks Internasional (PUTI) Q2 [Contract number: NKB-4264/UN2.RST/HKP.05.00/2020].
Publisher Copyright:
© 2022 Elsevier Ltd and Techna Group S.r.l.
PY - 2022/3/15
Y1 - 2022/3/15
N2 - Heterocyclic compounds such as spirooxindole, with five rings containing nitrogen, have an important role in the realm of medicine. This study aims to synthesize the spirooxindole derivative compounds using Fe3O4/graphene oxide (GO) nanocomposite as the catalyst. The GO sample was synthesized by Hummers' method, followed by the insertion of Fe3O4 into the graphene oxide layers by the co-precipitation method. Both XRD and FTIR analyses reveal that GO and Fe3O4/GO samples have been successfully formed. SEM-EDX micrograph supported by TEM image indicates that the Fe3O4 nanoparticles in the composite have excellent dispersibility, attributable to the existence of the GO sheets. The evaluation of the ability of Fe3O4/GO as a catalyst in the synthesis of spirooxindole derivatives was carried out by the one-pot three-component method. The reaction yield shows that Fe3O4/GO was a suitable and reusable catalyst in this reaction.
AB - Heterocyclic compounds such as spirooxindole, with five rings containing nitrogen, have an important role in the realm of medicine. This study aims to synthesize the spirooxindole derivative compounds using Fe3O4/graphene oxide (GO) nanocomposite as the catalyst. The GO sample was synthesized by Hummers' method, followed by the insertion of Fe3O4 into the graphene oxide layers by the co-precipitation method. Both XRD and FTIR analyses reveal that GO and Fe3O4/GO samples have been successfully formed. SEM-EDX micrograph supported by TEM image indicates that the Fe3O4 nanoparticles in the composite have excellent dispersibility, attributable to the existence of the GO sheets. The evaluation of the ability of Fe3O4/GO as a catalyst in the synthesis of spirooxindole derivatives was carried out by the one-pot three-component method. The reaction yield shows that Fe3O4/GO was a suitable and reusable catalyst in this reaction.
KW - Antioxidant activity
KW - FeO/graphene oxide
KW - Heterogenous catalyst
KW - Nanocomposite material
KW - Spirooxindole derivatives
KW - Structural analysis
UR - http://www.scopus.com/inward/record.url?scp=85126540017&partnerID=8YFLogxK
U2 - 10.1016/j.ceramint.2022.03.090
DO - 10.1016/j.ceramint.2022.03.090
M3 - Article
AN - SCOPUS:85126540017
SN - 0272-8842
VL - 48
SP - 18316
EP - 18323
JO - Ceramics International
JF - Ceramics International
IS - 13
ER -