Low resonance frequency analyzer (Lrfa) as a potential tool for evaluating dental implant osseointegration

Dental implant treatment is one of the best alternatives in replacing missing teeth. Osseointegration is an important factor in determining its success, assessed from process that occurs between implant and bone as the criterion. Histomorphometry is the most accurate osseointegration evaluation method. The aim of this research was to develop and evaluate whether Low Resonance Frequency Analyzer (LRFA) could be used as an alternative tool for osseointegration evaluation. This study conducted in two stages; LRFA fabrication and diagnostic testing. Osseointegration process evaluation was the second stage. Six male Macaque fascicularis aged about 6 years, weighing from 4.5 to 6 kg were the research subject. Evaluation of were performed through clinical examination and LRFA measurement on the first and second week, then once every month until the fourth month. Animals were sacrificed after the fourth month and histomorphometric examination was performed. The result of histomorphometric examination was compared with LRFA measurement using Pearson correlation coefficient. ROC curve of diagnostic test showed that sensitivity and specificity of LRFA was 90.2% (optimal values). Statistical analysis showed strong correlation between LRFA measurement and histomorphometric examination (R=0.8, P < 0.5). With the result was as good as histomorphometric examination, therefore LRFA is an alternative osseointegration evaluation tool.