Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status

Putri Lenggogeny; Sri Lelyati C. Masulili; Fatimah M. Tadjoedin; Basuni Radi

doi:10.1063/1.4976773

Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

Periodontitis is a risk factor for coronary heart disease (CHD). Both diseases are an inflammatory diseases and have the same potential pathogenic mechanisms. Interleukin-1β as a pro-inflammatory main cytokine, can be found in this both diseases. Gingival crevicular fluid (GCF) derived from the serum of gingival sulcus, affected by inflammatory mechanism and the amount of this fluid will increase in that situation. Objective: To analyze the relationship of interleukin-1β levels in gingival crevicular fluid (GCF) of CHD and non-CHD patients with periodontal status. Methods: Oral clinical examination (plaque index, bleeding on probing, pocket depth and clinical attachment loss) for 35 subjects with CHD and 35 non CHD were checked, laboratory test to measure the levels of Interleukin-1β was checked with enzyme-linked immunosorbent assay (ELISA). Results: There was no significant differences between interleukin-1β levels in CHD and non-CHD patients (p>0.05); there was no significant difference between the level of Interleukin-1β with periodontal status in CHD and control (non CHD) patients (p>0.05). Conclusions: levels of Interleukin-1β in CHD patients do not have a relationships with plaque index, pocket depth and clinical attachment loss, but has a relationships with bleeding on probing.

Original language	English
Title of host publication	Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publication	Proceedings of the 1st International Symposium of Biomedical Engineering, ISBE 2016
Editors	Yudan Whulanza, Sugeng Supriadi, Muhamad Sahlan, Basari
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735414853
DOIs	https://doi.org/10.1063/1.4976773
Publication status	Published - 21 Feb 2017
Event	1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016 - Depok City, Indonesia Duration: 31 May 2016 → 1 Jun 2016

Publication series

Name	AIP Conference Proceedings
Volume	1817
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016
Country/Territory	Indonesia
City	Depok City
Period	31/05/16 → 1/06/16

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

coronary artery disease
gingival crevicular fluid
interleukin-1β
periodontal status

Access to Document

10.1063/1.4976773

Cite this

Lenggogeny, P., Masulili, S. L. C., Tadjoedin, F. M., & Radi, B. (2017). Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status. In Y. Whulanza, S. Supriadi, M. Sahlan, & Basari (Eds.), Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 1st International Symposium of Biomedical Engineering, ISBE 2016 Article 030004 (AIP Conference Proceedings; Vol. 1817). American Institute of Physics Inc.. https://doi.org/10.1063/1.4976773

Lenggogeny, Putri ; Masulili, Sri Lelyati C. ; Tadjoedin, Fatimah M. et al. / Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status. Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 1st International Symposium of Biomedical Engineering, ISBE 2016. editor / Yudan Whulanza ; Sugeng Supriadi ; Muhamad Sahlan ; Basari. American Institute of Physics Inc., 2017. (AIP Conference Proceedings).

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title = "Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status",

abstract = "Periodontitis is a risk factor for coronary heart disease (CHD). Both diseases are an inflammatory diseases and have the same potential pathogenic mechanisms. Interleukin-1β as a pro-inflammatory main cytokine, can be found in this both diseases. Gingival crevicular fluid (GCF) derived from the serum of gingival sulcus, affected by inflammatory mechanism and the amount of this fluid will increase in that situation. Objective: To analyze the relationship of interleukin-1β levels in gingival crevicular fluid (GCF) of CHD and non-CHD patients with periodontal status. Methods: Oral clinical examination (plaque index, bleeding on probing, pocket depth and clinical attachment loss) for 35 subjects with CHD and 35 non CHD were checked, laboratory test to measure the levels of Interleukin-1β was checked with enzyme-linked immunosorbent assay (ELISA). Results: There was no significant differences between interleukin-1β levels in CHD and non-CHD patients (p>0.05); there was no significant difference between the level of Interleukin-1β with periodontal status in CHD and control (non CHD) patients (p>0.05). Conclusions: levels of Interleukin-1β in CHD patients do not have a relationships with plaque index, pocket depth and clinical attachment loss, but has a relationships with bleeding on probing.",

keywords = "coronary artery disease, gingival crevicular fluid, interleukin-1β, periodontal status",

author = "Putri Lenggogeny and Masulili, \{Sri Lelyati C.\} and Tadjoedin, \{Fatimah M.\} and Basuni Radi",

note = "Publisher Copyright: {\textcopyright} 2017 Author(s).; 1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016 ; Conference date: 31-05-2016 Through 01-06-2016",

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Lenggogeny, P, Masulili, SLC , Tadjoedin, FM & Radi, B 2017, Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status. in Y Whulanza, S Supriadi, M Sahlan & Basari (eds), Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 1st International Symposium of Biomedical Engineering, ISBE 2016., 030004, AIP Conference Proceedings, vol. 1817, American Institute of Physics Inc., 1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016, Depok City, Indonesia, 31/05/16. https://doi.org/10.1063/1.4976773

Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status. / Lenggogeny, Putri; Masulili, Sri Lelyati C.; Tadjoedin, Fatimah M. et al.
Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 1st International Symposium of Biomedical Engineering, ISBE 2016. ed. / Yudan Whulanza; Sugeng Supriadi; Muhamad Sahlan; Basari. American Institute of Physics Inc., 2017. 030004 (AIP Conference Proceedings; Vol. 1817).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status

AU - Lenggogeny, Putri

AU - Masulili, Sri Lelyati C.

AU - Tadjoedin, Fatimah M.

AU - Radi, Basuni

PY - 2017/2/21

Y1 - 2017/2/21

N2 - Periodontitis is a risk factor for coronary heart disease (CHD). Both diseases are an inflammatory diseases and have the same potential pathogenic mechanisms. Interleukin-1β as a pro-inflammatory main cytokine, can be found in this both diseases. Gingival crevicular fluid (GCF) derived from the serum of gingival sulcus, affected by inflammatory mechanism and the amount of this fluid will increase in that situation. Objective: To analyze the relationship of interleukin-1β levels in gingival crevicular fluid (GCF) of CHD and non-CHD patients with periodontal status. Methods: Oral clinical examination (plaque index, bleeding on probing, pocket depth and clinical attachment loss) for 35 subjects with CHD and 35 non CHD were checked, laboratory test to measure the levels of Interleukin-1β was checked with enzyme-linked immunosorbent assay (ELISA). Results: There was no significant differences between interleukin-1β levels in CHD and non-CHD patients (p>0.05); there was no significant difference between the level of Interleukin-1β with periodontal status in CHD and control (non CHD) patients (p>0.05). Conclusions: levels of Interleukin-1β in CHD patients do not have a relationships with plaque index, pocket depth and clinical attachment loss, but has a relationships with bleeding on probing.

AB - Periodontitis is a risk factor for coronary heart disease (CHD). Both diseases are an inflammatory diseases and have the same potential pathogenic mechanisms. Interleukin-1β as a pro-inflammatory main cytokine, can be found in this both diseases. Gingival crevicular fluid (GCF) derived from the serum of gingival sulcus, affected by inflammatory mechanism and the amount of this fluid will increase in that situation. Objective: To analyze the relationship of interleukin-1β levels in gingival crevicular fluid (GCF) of CHD and non-CHD patients with periodontal status. Methods: Oral clinical examination (plaque index, bleeding on probing, pocket depth and clinical attachment loss) for 35 subjects with CHD and 35 non CHD were checked, laboratory test to measure the levels of Interleukin-1β was checked with enzyme-linked immunosorbent assay (ELISA). Results: There was no significant differences between interleukin-1β levels in CHD and non-CHD patients (p>0.05); there was no significant difference between the level of Interleukin-1β with periodontal status in CHD and control (non CHD) patients (p>0.05). Conclusions: levels of Interleukin-1β in CHD patients do not have a relationships with plaque index, pocket depth and clinical attachment loss, but has a relationships with bleeding on probing.

KW - coronary artery disease

KW - gingival crevicular fluid

KW - interleukin-1β

KW - periodontal status

UR - https://www.scopus.com/pages/publications/85016084930

U2 - 10.1063/1.4976773

DO - 10.1063/1.4976773

M3 - Conference contribution

AN - SCOPUS:85016084930

T3 - AIP Conference Proceedings

BT - Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices

A2 - Whulanza, Yudan

A2 - Supriadi, Sugeng

A2 - Sahlan, Muhamad

A2 - Basari, null

PB - American Institute of Physics Inc.

T2 - 1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016

Y2 - 31 May 2016 through 1 June 2016

ER -

Lenggogeny P, Masulili SLC , Tadjoedin FM , Radi B. Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status. In Whulanza Y, Supriadi S, Sahlan M, Basari, editors, Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 1st International Symposium of Biomedical Engineering, ISBE 2016. American Institute of Physics Inc. 2017. 030004. (AIP Conference Proceedings). doi: 10.1063/1.4976773

Levels of interleukin-1β in gingival crevicular fluid in patients with coronary heart disease and its relationship to periodontal status

Abstract

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UN SDGs

Keywords

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