Lateriflorone, a cytotoxic spiroxalactone with a novel skeleton, from Garcinia lateriflora Bl.

Soleh Kosela, Shu Geng Cao, Xiao Hua Wu, Jagadese J. Vittal, Tony Sukri, Masdianto, Swee Hock Goh, Keng Yeow Sim

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

Lateriflorone (1), a cytotoxic natural product with an unprecedented spiroxalactone skeleton isolated from Garcinia lateriflora, has been characterized by NMR and X-ray crystallography studies as 6,21-bis(3- methylbut-2-enyl)-19-hydroxy-2,2,23,23-tetramethyl-13,15,22-trioxaspiro[6,7- dihydro-2H-chromene-7,4'-tetracyclo[7.4.1.02,7.02,11]tetradecane]-17- ene-5,8,16,20-tetraone.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number1
DOIs
Publication statusPublished - 1 Jan 1999

Keywords

  • Cytotoxicity
  • Garcinia
  • Lateriflorone
  • NMR

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