Knowledge, attitudes, and practices regarding Covid-19 and their relationship with Covid-19 booster vaccination status among women with infertility

Objective: To elucidate the relationship among knowledge, attitudes, and practices regarding Covid-19 and their relationship with booster vaccination status among women with infertility. Methods: This questionnaire-based cross-sectional study was performed online and offline among women with infertility who visited an infertility clinic in Jakarta, Indonesia. We assessed the patient’s knowledge, attitudes, and practices regarding Covid-19 and their relationship with booster vaccination status and sociodemographic profile. Results: A total of 178 subjects participated in this study, and most participants (92.6%) had received booster Covid-19 vaccines. From the questionnaire, 74.2% had good knowledge, and 99.4% had good attitudes regarding Covid-19; however, only 57.9% of patients had good practices. A weak positive correlation existed between knowledge and attitudes (r=0.11, P=0.13) and a moderate negative correlation between attitudes and practices (r=-0.44, P=0.56). Participants’ knowledge about vaccines and infertility was correlated with booster vaccination status (P=0.04). Academic background (P=0.01) and attitudes (P=0.01) were also correlated with booster vaccination status. The significant determinants of hesitance of receiving Covid-19 booster vaccines were high school education or below (OR=0.08, 95% CI 0.02-0.36) and poor practices (OR=0.21, 95% CI 0.05-0.95). Conclusions: The majority of the participants had received the Covid-19 booster vaccine and had good knowledge and attitudes but poor practices regarding Covid-19. Most participants had poor knowledge about the relationship between infertility and the Covid-19 vaccine. The general population should be more informed and reminded about practices to prevent Covid-19 and the relationship between vaccination and fertility to increase the number of people who receive Covid-19 booster vaccines.