Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium-host interactions

B. M. Bachtiar, Peter J. Coloe, Benjamin N. Fry

Research output: Contribution to journalArticlepeer-review

58 Citations (Scopus)

Abstract

Campylobacter jejuni is a common cause of bacterial enteritis. The surface capsular polysaccharides are important for this bacterium to survive in the environment, but little is known about their involvement in bacterium-host interactions. This study showed that the C. jejuni capsular polysaccharides play an important role in adherence to and invasion of human embryonic epithelial cells. However, no significant role of capsular polysaccharides was shown in colonization of the chicken gut.

Original languageEnglish
Pages (from-to)149-154
Number of pages6
JournalFEMS Immunology and Medical Microbiology
Volume49
Issue number1
DOIs
Publication statusPublished - 1 Feb 2007

Keywords

  • Bacterium-host interaction
  • Campylobacter jejuni
  • kpsE gene

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