Jumlah Kelenjar Limfe sebagai Prediktor Kesintasan Penderita Kanker Serviks yang Dilakukan Histerektomi Radikal dan Limfadenektomi

Rm Ali Fadhly, Sigit Purbadi

Research output: Contribution to journalArticlepeer-review


Cervical cancer is the fourth most common cancer in women in the world. In Indonesia, there were 838 cases of cervical cancer in 2013 and increased to 1632 cases in 2014. Based on the prognosis and treatment, cervicalcancer is divided into two groups: early stage (IA-IIA) and advanced stages (IIB-IVB). The treatment of earlystage cervical cancer is surgery or radiotherapy. Surgery means a radical hysterectomy and lymphadenectomy.In young patients with early stage, generally performed radical hysterectomy because ovaries and vagina need tobe maintained. Radical hysterectomy and lymphadenectomy is preferable to radiotherapy because radiotherapycan permanently damage normal tissue at the site of the neoplasm. Lymph node involvement is one of thefactors that affect the survival of cervical cancer. 5-year survival rate of cervical cancer decreased by 25-60% ifthere is metastasis to the lymph nodes. Based on the status of nodules, number 5-year disease-free survival of80.9-83.3% in patients with positive nodes and 90.2-97.8% in negative nodules. Cervical cancer survival rate is still low, therefore its necessary to have a predictor of survival in order to do further action to improve survival. The amount of removal of the lymph nodes may improve survival, but the relationship between the number oflymph nodes removal and survival for early stage of cervical cancer patients is unknown. Research is neededto determine the number of lymph nodes were extracted as a predictor of patient’s survival with cervical cancerwho performed a radical hysterectomy and lymphadenectomy.
Original languageIndonesian
JournaleJournal Kedokteran Indonesia
Issue number3
Publication statusPublished - 2015

Cite this