Introduction: It is known that stress is one of the risk factors for Temporomandibular Disorders (TMD). Studies of TMD in people with high levels of job stress are lacking. The primary reason for choosing accountants for this study is because these individuals work under considerable stress. Objective:The aim of this study was to investigate the relationship between intensity and frequency of job stress and the occurrence of TMD in accountants in Jakarta. Methods:A cross sectional study was performed of 116 accountants aged 21-50 in Jakarta. The subjects were asked to fill two kinds of questionnaire. The first was the Job Stress Survey questionnaire (JSS)designed by Vagg and Spielberger in 1998 to examine the intensity and frequency level of job stress. The second was the TMD Diagnostic Indexdeveloped by Himawan et al. in 2006to assess the TMD. A cross tabulation was done between the intensity level of job stress, the frequency level of job stress, and TMD occurrence. The study received ethical clearance from Faculty of Dentistry, Universitas Indonesia. Results: Fisher’s Exact test showed that there was a significant relationship between intensity of job stress and the occurrence of TMD in accountants (p = 0.003). Chi square test showed that there was a significant relationship between frequency of job stress and the occurrence of TMD in accountants (p = 0.032). Conclusion:There is a relationship between intensity and frequency of job stress, and the occurrence of TMD in accountants.