IS THE ANTIMICROBIAL RESISTANCE OF ESCHERICHIA COLI. PATHOGEN IN CHILDREN WITH DIARRHEAL INFECTION STILL A CONCERN IN INDONESIA? AN UPDATED REVIEW

Omnia Amir Osman Abdelrazig, Fadilah Fadilah, Badriul Hegar, Yulia Rosa Saharman

Research output: Contribution to journalReview articlepeer-review

Abstract

Childhood diarrhea is increasing in developing countries like Indonesia, affecting 6.7% of children under five largely due to Escherichia coli. Method: This review aims to provide an updated review on the latest information on childhood diarrhea in Indonesia and Escherichia coli antibiotic resistance from recent research sources till June 2023 from databases like PubMed, Scopus, and Google Scholar using specific search terms such as diarrhea, children, Morbidity, mortality, Indonesia, Escherichia Coli, and Antibiotic Resistance. It includes articles from nationally and internationally accredited peer-reviewed health journals in both English and Indonesian. Results: Based on the studies we reviewed, it has been proven that under-five diarrhea is the most common cause of death in children in Indonesia. Our literature analysis also revealed a potential link between gender and the occurrence of diarrhea in children. Furthermore, our analysis identified risk factors, including contaminated water, inadequate sanitation, poor hygiene and suboptimal food hygiene practices as the primary causes of childhood diarrhea in Indonesia. Conversely, other studies reviewed in this paper reveal that E. coli is the most common pathogen responsible for childhood diarrhea in Indonesia. Our study evaluation further reveals that Escherichia coli exhibits a high resistance rate, possibly due to the widespread misuse of antibiotics in the country. Conclusion: Indonesia's under-five diarrhea is a leading cause of child mortality, with multiple risk factors including sanitation and Escherichia coli Pathogen.

Original languageEnglish
Pages (from-to)533-553
Number of pages21
JournalBulletin of Pharmaceutical Sciences. Assiut
Volume47
Issue number1
DOIs
Publication statusPublished - Jun 2024

Keywords

  • Antimicrobial Resistance
  • Children
  • Diarrhea
  • Escherichia Coli
  • Indonesia

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