Iridium oxide (IV) nanoparticle-based lateral flow immunoassay

Daniel Quesada-González, Amadeo Sena-Torralba, Wiyogo Prio Wicaksono, Alfredo de la Escosura-Muñiz, Tribidasari A. Ivandini, Arben Merkoçi

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

Lateral flow biosensors are paper-based devices that allow the detection of different types of analytes with quickness, robustness and selectivity, without leaving behind paper sensors benefits as low-cost, recyclability and sustainability. Nanomaterials have been widely reported in lateral flow biosensors, offering new sensing strategies based on optical or electrical detection techniques. Looking for other advantageous nanomaterials, we propose for the first time the use of iridium oxide (IV) nanoparticles in lateral flow assays for the detection of human immunoglobulin as a model protein. These nanoparticles can be easily prepared and conjugated with biomarkers. Their dark blue color gives a high contrast against the white background of the strips being in this way excellent labels.

Original languageEnglish
Pages (from-to)132-135
Number of pages4
JournalBiosensors and Bioelectronics
Volume132
DOIs
Publication statusPublished - 1 May 2019

Keywords

  • Iridium oxide nanoparticles
  • Lateral flow immunoassay
  • Mobile phone sensing
  • Paper-based biosensor

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