Investigating the weight ratio variation of alginate-hydroxyapatite composites for vertebroplasty method bone filler material

Gusti Ruri Lestari, Akhmad Herman Yuwono, Nofrijon Bin Imam Sofyan, Ghiska Ramahdita

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

One of the newly developed methods for curing spinal fracture due to osteoporosis is vertebroplasty. The method is basically based on injection of special material directly to the fractured spine in order to commence the formation of new bone. Therefore, appropriate injectable materials are very important to the curing success. In this study, injectable alginate-hydroxyapatite (HA) composites were fabricated varying the weight percentage of alginate upon synthesis procedure. The result of injection capability and compressive tests as well as Fourier transform infrared (FTIR) spectroscopy and scanning electron microscope (SEM) suggested that bone filler composite containing 60 wt% alginate is the optimum composition obtaining a compressive modulus up to 0.15 MPa, injection capability of more than 85% and morphology with uniform porous and fibrous structure. This injectable composite fabrication process can be used for the development of injectable materials system for vertebroplasty method.

Original languageEnglish
Title of host publicationBiomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publicationProceedings of the 1st International Symposium of Biomedical Engineering, ISBE 2016
EditorsYudan Whulanza, Sugeng Supriadi, Muhamad Sahlan, Basari
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735414853
DOIs
Publication statusPublished - 21 Feb 2017
Event1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016 - Depok City, Indonesia
Duration: 31 May 20161 Jun 2016

Publication series

NameAIP Conference Proceedings
Volume1817
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016
CountryIndonesia
CityDepok City
Period31/05/161/06/16

Keywords

  • alginate
  • bone filler
  • hydroxyapatite
  • injectable
  • osteoporosis
  • vertebroplasty

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