TY - GEN
T1 - Interpretation of human tooth nerve fiber image
T2 - 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011
AU - Surya, Muhammad Rabindra
AU - Rusdi, Mellawaty
AU - Arymurthy, Aniati Murni
AU - Soerono-Akbar, Siti Mardewi
AU - Santosa, Didi Nugroho
PY - 2011
Y1 - 2011
N2 - Tooth pain is the most common form of orofacial pain. Tooth sensory system is very sensitive to detect noxious stimulus. Most of sensory stimulus, which come from pulp afferent fibres will cause pain sensation. Action potential transmits the stimulus from periphery to the central. Sodium channels have an important role to generate and propagate the action potential. One of its isoforms, Nav1.8, has only found in sensory nerve, especially in nociceptive neuron that deliver pain stimulus. In myelinated neuron such as A-δ fibres, sodium channels located in high density on the node of Ranvier. The density of sodium channel Nav1.8 has a strong relation with tooth sensitivity. We implement method to detect nodes of Ranvier and detect Nav1.8 as our region of interest. In this paper, threshold and local enhancement is used for nodes of Ranvier detection and improvement of Euclidean path for sodium channels Nav1.8 detection.
AB - Tooth pain is the most common form of orofacial pain. Tooth sensory system is very sensitive to detect noxious stimulus. Most of sensory stimulus, which come from pulp afferent fibres will cause pain sensation. Action potential transmits the stimulus from periphery to the central. Sodium channels have an important role to generate and propagate the action potential. One of its isoforms, Nav1.8, has only found in sensory nerve, especially in nociceptive neuron that deliver pain stimulus. In myelinated neuron such as A-δ fibres, sodium channels located in high density on the node of Ranvier. The density of sodium channel Nav1.8 has a strong relation with tooth sensitivity. We implement method to detect nodes of Ranvier and detect Nav1.8 as our region of interest. In this paper, threshold and local enhancement is used for nodes of Ranvier detection and improvement of Euclidean path for sodium channels Nav1.8 detection.
KW - Detection
KW - Fluorescent
KW - Fusion
KW - Nodes of Ranvier
KW - Paranodes
UR - http://www.scopus.com/inward/record.url?scp=79960119238&partnerID=8YFLogxK
U2 - 10.1109/icbbe.2011.5780193
DO - 10.1109/icbbe.2011.5780193
M3 - Conference contribution
AN - SCOPUS:79960119238
SN - 9781424450893
T3 - 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011
BT - 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011
Y2 - 10 May 2011 through 12 May 2011
ER -