@inproceedings{7196fb8af67e4e3c913724cd1a9289d0,
title = "Interaction between dimethyldioctadecylammonium bromide-modified PLGA microspheres and hyaluronic acid",
abstract = "In application of intravitreal injection, an extended drug delivery system is desired so that the frequency of injection to treat diabetic retinopathy may be reduced. Poly(lactic-co-glycolic acid) polymer (PLGA) was used to encapsulate a model drug in the form of microspheres. The zeta potential of dimethyldioctadecylammonium bromide (DDAB)-modified PLGA microspheres in water was proportional to the DDAB concentration used in the preparation step, up to +57.8 mV. The scanning electron microscope pictures and the zeta potential data (SEM) confirmed that the surface of the PLGA has been modified by the cationic surfactant and that electrostatic interaction between the positively charged microspheres and the negatively charged vitreous were present.",
keywords = "DDAB, PLGA, cationic surfactant, controlled drug release, diabetic retinopathy, hyaluronic acid, microparticle, zeta potential",
author = "Kamarza Mulia and Devi and Krisanti, {Elsa Anisa}",
note = "Publisher Copyright: {\textcopyright} 2017 Author(s).; 1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016 ; Conference date: 31-05-2016 Through 01-06-2016",
year = "2017",
month = feb,
day = "21",
doi = "10.1063/1.4976768",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Yudan Whulanza and Sugeng Supriadi and Muhamad Sahlan and Basari",
booktitle = "Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices",
address = "United States",
}