Objective: This study was aimed at developing and testing an instrument that can be used to evaluate self-efficacy for mobilization. Method: Phase 1 was a qualitative study carried out through interviews. Phase 2 involved determining the content validity and testing the instrument legibility. Phase 3 involved ascertaining construct validity through a first order confirmatory factor analysis. Results: In phase 1, seven themes were identified and used as bases for establishing the indicators of each self-efficacy dimension. In phase 2, a content validity 0.75–1 was obtained. In phase 3, valid items that measure the level, strength, and generality dimensions have four, six, and seven items, respectively. Conclusion: The end product of the study was a concise and valid instrument that measures the self-efficacy of the patient for mobilization during hospitalization.