TY - JOUR
T1 - Influence of Microwave Irradiation Time and Cross-Linker Additions on Synthesis of Hydroxyapatite-Alginate (HA-Alginate) Composite
AU - Nuha, Nuha
AU - Nurlely, Nurlely
AU - Sari, Y. W.
N1 - Funding Information:
This work is supported by Hibah PITTA B 2019 funded by DRPM Universitas Indonesia with contract no NKB-0653/UN2.R3.1/HKP.05.00/2019, awarded to Dr. Nurlely and Dr. Yessie Widya Sari for their assistance in this research, and also thanks to Kementrian Riset dan Teknologi for the Saintek 2018 Graduate Scholarship.
Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/6/15
Y1 - 2020/6/15
N2 - Composite was prepared with hydroxyapatite and commercial alginate by microwave irradiation method. Hydroxyapatite is a calcium phosphate compound which has a similar chemical composition of human bone tissue. In this study, hydroxyapatite-alginate (HA-Alginate) composite with the mass ratio of 80:20 (HA-Alginate) was synthesized using microwave irradiation for 10 min and 15 min. The power source was settled at 360 W. The functional groups of the composites were examined by FTIR (Fourier Transform Infrared Spectroscopy). The crystallite size and phase purity of HA were determined by XRD (X-Ray Diffraction). The FTIR and XRD results confirmed the existence of alginate and HA in the composites. The crystallite size of the HA increased with the increasing microwave irradiation time. This study also investigated the presence of CaCl2 as cross-linker agent at difference concentration (0.01 M; 0.03M; and 0.05M). The results showed the crystallite size of the HA increased by adding cross-linker from 10.806 nm (without cross-linker) to 13.081 nm (with CaCl2 0.05M) and a composite mass increased from 4.84 gram (without cross-linker) to 5.10 gram (with addition 0.05 M CaCl2).
AB - Composite was prepared with hydroxyapatite and commercial alginate by microwave irradiation method. Hydroxyapatite is a calcium phosphate compound which has a similar chemical composition of human bone tissue. In this study, hydroxyapatite-alginate (HA-Alginate) composite with the mass ratio of 80:20 (HA-Alginate) was synthesized using microwave irradiation for 10 min and 15 min. The power source was settled at 360 W. The functional groups of the composites were examined by FTIR (Fourier Transform Infrared Spectroscopy). The crystallite size and phase purity of HA were determined by XRD (X-Ray Diffraction). The FTIR and XRD results confirmed the existence of alginate and HA in the composites. The crystallite size of the HA increased with the increasing microwave irradiation time. This study also investigated the presence of CaCl2 as cross-linker agent at difference concentration (0.01 M; 0.03M; and 0.05M). The results showed the crystallite size of the HA increased by adding cross-linker from 10.806 nm (without cross-linker) to 13.081 nm (with CaCl2 0.05M) and a composite mass increased from 4.84 gram (without cross-linker) to 5.10 gram (with addition 0.05 M CaCl2).
UR - http://www.scopus.com/inward/record.url?scp=85086804463&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/1505/1/012058
DO - 10.1088/1742-6596/1505/1/012058
M3 - Conference article
AN - SCOPUS:85086804463
SN - 1742-6588
VL - 1505
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
IS - 1
M1 - 012058
T2 - 3rd Annual Scientific Meeting on Medical Physics and Biophysics, PIT-FMB in conjunction with the 17th South-East Asia Congress of Medical Physics, SEACOMP 2019
Y2 - 8 August 2019 through 10 August 2019
ER -