Indication and Procedures of Pleurodesis

Zulkifli Amin, Masna, Ina Ariani Kirana

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The aim of pleurodesis is to achieve symphysis between visceral and parietal pleural layers, preventing accumulation of either air or fluid in pleural space. Its main indications are malignant pleural effusions and spontaneous pneumothorax. There is no absolute contraindication for pleurodesis. However, several matters need to be taken in cosideration to achieve optimal therapeutic effect. The right choice of technique, sclerosing agent, and criteria for patients selection are important and controversial issues. Many sclerosing agents have been introduced, such as tetracyclin, doxycyclin, minocyclin, bleomycin, quinacrin, and patient’s own blood, but talc is most often used because it is economis, effective, and cause relatively minor complication. Talc pleurodesis does not require general anesthesia or tracheal intubation. Before the procedure, patient evaluation such as chest x-ray, bronchoscopy if possible, reviewing patient’s history of illness, and physical findings, is evaluated. Talc is instilled into the pleural cavity through the chest tube and the patient is asked to breath several times so that the talc slurry enters the cavity. Patient monitoring after the procedur includes chest x-ray, vital signs monitoring, daily chest tube drainage, air leakage, and pain control. Possible complication includes pain, tachycardia, tachypnea, pneumonitis, fever, incomplete lung inflation, and allergic reaction.Keywords: pleurodesis, malignant pleural effusion, spontaneous pneumothorax
Original languageEnglish
JournalJournal of the Indonesian Medical Association
Issue number4
Publication statusPublished - 2007


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