TY - JOUR
T1 - Implementation of Hierarchical Clustering Method in Analyzing Genetic Relationship on DNA SARS-CoV-2 Sequences
AU - Banjarnahor, E.
AU - Bustamam, A.
AU - Mangunwardoyo, W.
AU - Sarwinda, D.
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2021/3/23
Y1 - 2021/3/23
N2 - In mid-September of 2020, WHO released data starting that more than 28 million people worldwide have contracted coronavirus. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the full name coronavirus, specifically Covid-19. This virus attacks the human respiratory system and can cause infection in the human lungs and even death. WHO noted that more than 900 thousand people worldwide have died due to being infected with the coronavirus. In Indonesia, more than 210 thousand people have been infected by the coronavirus, and more than 8,5 thousand of them have died. Based on this data, it is necessary to analyze the coronavirus's kinship to reduce the spreading. This research uses The Euclidean distance in determining the distance matrix. This research will then use the Hierarchical Clustering method for analyzing the genetic relationship on DNA SARS-CoV-2 sequences. This research will take samples of SARS-CoV-2 DNA sequences from 20 countries infected. From the simulation result, the ancestors of SARS-CoV-2 coming from China. Besides, it also found that the SARS-CoV-2 DNA sequence from Indonesia has the closest ancestor from Pakistan.
AB - In mid-September of 2020, WHO released data starting that more than 28 million people worldwide have contracted coronavirus. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the full name coronavirus, specifically Covid-19. This virus attacks the human respiratory system and can cause infection in the human lungs and even death. WHO noted that more than 900 thousand people worldwide have died due to being infected with the coronavirus. In Indonesia, more than 210 thousand people have been infected by the coronavirus, and more than 8,5 thousand of them have died. Based on this data, it is necessary to analyze the coronavirus's kinship to reduce the spreading. This research uses The Euclidean distance in determining the distance matrix. This research will then use the Hierarchical Clustering method for analyzing the genetic relationship on DNA SARS-CoV-2 sequences. This research will take samples of SARS-CoV-2 DNA sequences from 20 countries infected. From the simulation result, the ancestors of SARS-CoV-2 coming from China. Besides, it also found that the SARS-CoV-2 DNA sequence from Indonesia has the closest ancestor from Pakistan.
UR - http://www.scopus.com/inward/record.url?scp=85103435172&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/1811/1/012074
DO - 10.1088/1742-6596/1811/1/012074
M3 - Conference article
AN - SCOPUS:85103435172
SN - 1755-1307
VL - 1811
JO - IOP Conference Series: Earth and Environmental Science
JF - IOP Conference Series: Earth and Environmental Science
IS - 1
M1 - 012074
T2 - 2nd International Conference on Sciences and Technology Applications, ICOSTA 2020
Y2 - 3 November 2020
ER -