Hydroxyapatite Deposition on Modified Bacterial Cellulose Matrix

Farah Nurlidar, Emil Budianto, Darmawan Darwis, Sugiarto

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Summary Bacterial cellulose (BC), biosynthesized by bacteria, is an attractive biomaterial for bone regeneration due to its biocompatibility and good mechanical properties. However, BC is devoid of inorganic elements which are necessary for formation of chemical bonds with bone. Incorporation of inorganic phases such as hydroxyapatite (HA) into BC matrix may enhance bone regeneration. The aim of this study was to develop BC as a matrix for HA deposition. Absorption capacity is a key to incorporate calcium ion into BC and induces HA deposition. To enhance its absorption capacity, BC was modified using citric acid. The results showed that the incorporation of carboxylate groups into BC via reaction with citric acid improved its absorption capacity. X-ray diffraction (XRD) patterns of the modified BC after soaking treatments showed HA deposition with diffractions attributed to low crystalline HA at 2θ = 11.7°; 26.2°; 29.4°; 32.0°; 33.0°; 34.2°; and 46.6°. Furthermore, energy dispersive spectroscopy (EDS) analysis showed that the average Ca/P ratio was 1.12.

Original languageEnglish
Pages (from-to)128-132
Number of pages5
JournalMacromolecular Symposia
Issue number1
Publication statusPublished - 1 Jul 2015


  • bacterial cellulose
  • biopolymers
  • citric acid
  • coconut water
  • hydroxyapatite


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