TY - JOUR
T1 - Hyaluronic Acid and Chlorine Dioxide on Post-odontectomy Swelling and Pain
T2 - A Randomised Controlled Trial
AU - Utomo, Yudy Ardilla
AU - Alifia, Jihan Fasya
AU - Sulistyani, Lilies Dwi
AU - Julia, Vera
AU - Ariawan, Dwi
AU - Reksoprodjo, Muhammad Ramaditto
N1 - Funding Information:
We thank drg. Muhammad Arya Yunial and drg Andi Surya Dharma for being the operators in this study.
Publisher Copyright:
© 2023, Journal of International Dental and Medical Research. All Rights Reserved.
PY - 2023
Y1 - 2023
N2 - Gels containing hyaluronic acid (HA) and chlorine dioxide (ClO2) can be used to treat postodontectomy swelling and pain. There is minimal study comparing the outcome of these preparations. This study aims to compare swelling and pain in post-odontectomy patients treated with HA and ClO2 gels. Material and methods: A RCT with three parallel arms were designed for this study. 165 patients with impacted third molar were included and allocated into HA-treated, ClO2-treated, and control group (n=55). The measurement is using Gabka and Matsumara technique and numeric rating scale. Data was collected during the same day, 2-days, and 7-days after surgery. Median pain scores on HA, ClO2 were lower than the control group on the same day (HA=6, ClO2=7, control=8; p<0.001) and on the second collection (HA=1, ClO2=2, control=3; p<0.001) and in the third collection were 0 in all groups (p<0.001). The median value of swelling was measured at 14.6 cm in all groups before surgery. On the second and third measurement, the median value of swelling on HA and ClO2 groups were minimally reduced compared to the control group (p>0.05). HA and ClO2 treatment reduces post-odontectomy pain score, and minimal effects on swelling were observed.
AB - Gels containing hyaluronic acid (HA) and chlorine dioxide (ClO2) can be used to treat postodontectomy swelling and pain. There is minimal study comparing the outcome of these preparations. This study aims to compare swelling and pain in post-odontectomy patients treated with HA and ClO2 gels. Material and methods: A RCT with three parallel arms were designed for this study. 165 patients with impacted third molar were included and allocated into HA-treated, ClO2-treated, and control group (n=55). The measurement is using Gabka and Matsumara technique and numeric rating scale. Data was collected during the same day, 2-days, and 7-days after surgery. Median pain scores on HA, ClO2 were lower than the control group on the same day (HA=6, ClO2=7, control=8; p<0.001) and on the second collection (HA=1, ClO2=2, control=3; p<0.001) and in the third collection were 0 in all groups (p<0.001). The median value of swelling was measured at 14.6 cm in all groups before surgery. On the second and third measurement, the median value of swelling on HA and ClO2 groups were minimally reduced compared to the control group (p>0.05). HA and ClO2 treatment reduces post-odontectomy pain score, and minimal effects on swelling were observed.
KW - Chlorine dioxide
KW - hyaluronic acid
KW - odontectomy
KW - oral surgery
KW - third-molar
UR - http://www.scopus.com/inward/record.url?scp=85165153205&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85165153205
SN - 1309-100X
VL - 16
SP - 772
EP - 777
JO - Journal of International Dental and Medical Research
JF - Journal of International Dental and Medical Research
IS - 2
ER -