Human Blastocyst Classification after in Vitro Fertilization Using Deep Learning

Ali Akbar Septiandri, Ade Jamal, Pritta Ameilia Iffanolida, Oki Riayati, Budi Wiweko

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

Embryo quality assessment after in vitro fertilization (IVF) is primarily done visually by embryologists. Variability among assessors, however, remains one of the main causes of the low success rate of IVF. This study aims to develop an automated embryo assessment based on a deep learning model using 1084 images from 1226 embryos. We captured the images using an inverted microscope at day 3 after fertilization. The images were labelled based on Veeck criteria that differentiate embryos to grade 1 to 5 based on the size of the blastomere and the grade of fragmentation. We compare the grading results from trained embryologists with our deep learning model to evaluate the performance. Our best model from a fine-tuned ResNet50 results in 91.79% accuracy. The model presented could be developed into an automated embryo assessment method in point-of-care settings.

Original languageEnglish
Title of host publication2020 7th International Conference on Advanced Informatics
Subtitle of host publicationConcepts, Theory and Applications, ICAICTA 2020
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781728180380
DOIs
Publication statusPublished - 8 Sep 2020
Event7th International Conference on Advanced Informatics: Concepts, Theory and Applications, ICAICTA 2020 - Virtual, Tokoname, Japan
Duration: 8 Sep 20209 Sep 2020

Publication series

Name2020 7th International Conference on Advanced Informatics: Concepts, Theory and Applications, ICAICTA 2020

Conference

Conference7th International Conference on Advanced Informatics: Concepts, Theory and Applications, ICAICTA 2020
Country/TerritoryJapan
CityVirtual, Tokoname
Period8/09/209/09/20

Keywords

  • deep learning
  • embryo grading
  • in vitro fertilization

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