TY - JOUR
T1 - High Proportion of Arsenic Detected in Bronchoalveolar Fluid among Newly Diagnosed Lung Cancer in Jakarta Indonesia
AU - Zaini, Jamal
AU - Ningtias, Indiane Putri
AU - Susanto, Agus Dwi
AU - Pradono, Prasenohadi
AU - Fadhillah, Muhammad Rizqy
AU - Andarini, Sita Laksmi
N1 - Publisher Copyright:
© This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License.
PY - 2023/10/1
Y1 - 2023/10/1
N2 - OBJECTIVE: This study aims to measure arsenic concentration in bronchoalveolar lavage fluid (BALF ) of newly diagnosed lung cancer and its corelation with clinical profiles. METHODS: This study is a cross-sectional study to identify arsenic levels in newly diagnosed lung cancer patients. Bronchoalveolar lavage fluid was taken during the bronchoscopy. Arsenic concentration was measured using an ICP-EOS spectrometer. RESULTS: Forty-two subjects who met inclusion criteria were recruited in this study. Arsenic metals were detected among 40% of subjects with mean, highest, and lowest values are 0.38 µg/L, 0.5 µg/L, and 0.3 µg/L, respectively. There is no significant difference between arsenic level and patients' demographic and clinical data. CONCLUSION: Arsenic was detected in BALF in majority of newly diagnosed lung cancer patients. Despite the insignificant relationship between arsenic level and patients characteristic, this results is evidence of which arsenic metal exposure in lung cancer during their lifetime and should raise public health awareness regarding mitigating the source of exposure and its potential as lung carcinogenic agent.
AB - OBJECTIVE: This study aims to measure arsenic concentration in bronchoalveolar lavage fluid (BALF ) of newly diagnosed lung cancer and its corelation with clinical profiles. METHODS: This study is a cross-sectional study to identify arsenic levels in newly diagnosed lung cancer patients. Bronchoalveolar lavage fluid was taken during the bronchoscopy. Arsenic concentration was measured using an ICP-EOS spectrometer. RESULTS: Forty-two subjects who met inclusion criteria were recruited in this study. Arsenic metals were detected among 40% of subjects with mean, highest, and lowest values are 0.38 µg/L, 0.5 µg/L, and 0.3 µg/L, respectively. There is no significant difference between arsenic level and patients' demographic and clinical data. CONCLUSION: Arsenic was detected in BALF in majority of newly diagnosed lung cancer patients. Despite the insignificant relationship between arsenic level and patients characteristic, this results is evidence of which arsenic metal exposure in lung cancer during their lifetime and should raise public health awareness regarding mitigating the source of exposure and its potential as lung carcinogenic agent.
KW - ARSENIC
KW - bronchoalveolar lavage
KW - Lung cancer
UR - http://www.scopus.com/inward/record.url?scp=85175272398&partnerID=8YFLogxK
U2 - 10.31557/APJCP.2023.24.10.3309
DO - 10.31557/APJCP.2023.24.10.3309
M3 - Article
C2 - 37898833
AN - SCOPUS:85175272398
SN - 1513-7368
VL - 24
SP - 3309
EP - 3313
JO - Asian Pacific journal of cancer prevention : APJCP
JF - Asian Pacific journal of cancer prevention : APJCP
IS - 10
ER -
