Hemoglobin Levels of Wistar Rats After Saluang Fish (Rasbora Spp) Powder Administration

It is estimated that 40% of children aged between 6-59 months experience anemia worldwide. In Indonesia prevalence of anemia in children under five reaches 38.5%, and 26.8% in children ages 5-14 years. Food first consumed by baby tends to support the absorption substance iron that causes Iron Deficiency Anemia (IDA). Saluang fish powder is a material food proven locally and contains high in protein, calcium, and substances iron. Research objectives : This study was to determine hemoglobin levels in Wistar Rats after being given a dose of Saluang fish powder. The method used is true experimental with post-test only design in Wistar Rats for 16 weeks in the Laboratory of Pharmacology, Universitas Muhammadiyah Palangkaraya. Control group divided into positive control group and negative control group. Whereas treatment group divided into of three groups which each given dose differently, low dose (0,36 g/ 200 g BW), moderate dose (0,54 g/ 200 gr BW), high dose (0,72 g/ 200 g BW) for 2 times a day intraperotoneal and standar feed ad libitum . The results show the average levels of hemoglobin group negative control was 19.617 mg/dL, and the group control positive 20.28 mg/dL. The average level of hemoglobin in the group in each treatment is that given dose light (19.65 grams/ dL), dose moderate (18.96 mg/dL), and dose high (20.33 mg/ dL). Statistical test results show there is no difference in average levels of hemoglobin in a low dose group (p-value=0.63), moderate dose group (p-value=0.77), and high dose group (p-value=0.189) with hemoglobin levels in the negative control group. However, there is a difference in average levels of hemoglobin in the treatment group(p-value=0.000) with average levels