Giant verruca vulgaris: A case report

Mona S. Haroen, Herliyani M. Purba, Eddy Kartadjukardi, Sri A. Sularsito

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Common wart is the most frequent clinical lesion caused by human papillomaviruses (HPVs). Giant, chronic, isolated, and solitary lesion is uncommon. We reported a case of giant verruca vulgaris in a 66 year-old man on left dorsal pedis that slowly enlarged and hardened in 10 years. It was a solitary hyperkeratotic verruca vulgaris, grey brownish in color, circumscribe, round, and 3×2.4×0.4 cm in size. Histopathologic examination revealed compact hyperkeratosis/orthokeratosis, many koilocytes in the granular and upper spinous layer, acanthosis, and elongated rete ridges that were pointing radially toward the center of the lesion. Polymerase chain reaction (PCR) and in situ hybridization failed to identify HPV DNA. The patient was successfully treated with salicylic acid 40% ointment.

Original languageEnglish
Pages (from-to)135-138
Number of pages4
JournalMedical Journal of Indonesia
Issue number2
Publication statusPublished - 1 Apr 2009


  • Hyperkeratosis
  • Orthokeratosis
  • Papilloma viruses


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