TY - GEN
T1 - Geometrical evaluation of CAM-configured thermoplastic polyurethane lattices for intervertebral disc replacements
AU - Nadhif, M. Hanif
AU - Irsyad, Muhammad
AU - Rahyussalim, A. J.
AU - Utomo, Muhammad Satrio
N1 - Funding Information:
This research was supported by the Universitas Indonesia through PUTI Grant 2020 (Contract Number: NKB-888/UN2.RST/HKP.05.00/2020) and by the Indonesian Institute of Science (LIPI). The authors also would like to thank the Research Center on Biomedical Engineering (RCBE), Universitas Indonesia for providing us the access to the stereomicroscope.
Publisher Copyright:
© 2021 Author(s).
PY - 2021/8/10
Y1 - 2021/8/10
N2 - Intervertebral discs (IVD) are prone to deformation due to higher stress that the discs can endure. Treatments for deformed IVDs include total disc replacements. Some studies concluded the superiority of spinal fusion compared to total disc replacement devices, either in the lumbar or cervical region. In current study, cuboid scaffolds made of thermoplastic polyurethane with lattice architecture were designed and configured using computer-aided manufacturing (CAM). The scaffolds were fabricated using fused filament fabrication. Process parameters were characterized and optimized to obtain scaffolds with uniform cells distribution. The struts at the top surface had average width values closer to the setpoints than the struts at the bottom surface, indicated by lower RMSE values for the struts at the top surface. However, the printing consistency in the same extrusion ratio at the bottom surface was higher than at the top surface, indicated by lower standard deviation values. Statistical analysis using standard deviation, RMSE, and Tukey's test showed that current scaffolds had non-uniform distribution between layers, which required further improvement.
AB - Intervertebral discs (IVD) are prone to deformation due to higher stress that the discs can endure. Treatments for deformed IVDs include total disc replacements. Some studies concluded the superiority of spinal fusion compared to total disc replacement devices, either in the lumbar or cervical region. In current study, cuboid scaffolds made of thermoplastic polyurethane with lattice architecture were designed and configured using computer-aided manufacturing (CAM). The scaffolds were fabricated using fused filament fabrication. Process parameters were characterized and optimized to obtain scaffolds with uniform cells distribution. The struts at the top surface had average width values closer to the setpoints than the struts at the bottom surface, indicated by lower RMSE values for the struts at the top surface. However, the printing consistency in the same extrusion ratio at the bottom surface was higher than at the top surface, indicated by lower standard deviation values. Statistical analysis using standard deviation, RMSE, and Tukey's test showed that current scaffolds had non-uniform distribution between layers, which required further improvement.
KW - Computer-aided manufacturing
KW - intervertebral disc
KW - lattice structure
KW - polyurethane
UR - http://www.scopus.com/inward/record.url?scp=85114011637&partnerID=8YFLogxK
U2 - 10.1063/5.0060049
DO - 10.1063/5.0060049
M3 - Conference contribution
AN - SCOPUS:85114011637
T3 - AIP Conference Proceedings
BT - Proceedings of the 4th International Seminar on Metallurgy and Materials, ISMM 2020
A2 - Khaerudini, Deni Shidqi
A2 - Darsono, Nono
A2 - Rhamdani, Ahmad Rizky
A2 - Utomo, Muhammad Satrio
A2 - Thaha, Yudi Nugraha
A2 - Kartika, Ika
A2 - Nugraha, Ahmad Ridwan Tresna
PB - American Institute of Physics Inc.
T2 - 4th International Seminar on Metallurgy and Materials: Accelerating Research and Innovation on Metallurgy and Materials for Inclusive and Sustainable Industry, ISMM 2020
Y2 - 19 November 2020 through 20 November 2020
ER -