@inproceedings{e959f0949c6d47219de10d016a0cc527,
title = "Genotoxicity and repair capability of DNA following the oral exposure to analgesic drugs: A review",
abstract = "Genotoxicity is a destructive effect from a substance that impairs genetic material in cells. Drugs are substances that can alter the systemic function, including analgesic drugs. Paracetamol, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids are three basic analgesic drugs that are often used to relieve the pain available in drug stores. Their action mechanism is known to be safe in a therapeutic dose and has a minimum side effect. Every chemical substance affects the cellular level, including DNA. The drugs have a mechanism to affect the cellular and DNA to control the drugs' damage, such as DNA repair. Each drug affects genetic material depend on the dose and time interval of administration.",
keywords = "diclofenac, genotoxicity, paracetamol, repair capability, tramadol",
author = "Langit, {Ken Sekar} and Auerkari, {Elza Ibrahim}",
note = "Funding Information: The authors wish to gratefully acknowledge financial support from the Universitas Indonesia to EIA. Publisher Copyright: {\textcopyright} 2021 Author(s).; 5th International Symposium of Biomedical Engineering, ISBE 2020 ; Conference date: 28-07-2020 Through 29-07-2020",
year = "2021",
month = mar,
day = "23",
doi = "10.1063/5.0047273",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Kenny Lischer and Sugeng Supriadi and Rahman, {Siti Fauziyah} and Yudan Whulanza",
booktitle = "5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices",
address = "United States",
}