Tangerang City is a developing township with high population growth (1.94%) and has high urbanization rate as well. The cases of diarrhea in Tangerang City were quite high. The objective of this study was to measure the diarhea susceptibility level based on the availability of clean water, the percentage of healthy household, the percentage of community personal hygiene, healthy public facilities and food vendors, and the coverage of public health services. The diarrhea susceptibility was catagorized into three levels that is high, moderate, and low. This study employs spatial analysis method based on sub-district level. Sub-districts with low level of diarhea susceptibility were Tangerang and Larangan, while sub-districts with high level of susceptibility were Cipondoh, Karawaci, and Cibodas. Others were in moderate level of diarrhea susceptibility. In the future, it is expected that Tangerang City could increase the availability of clean water facilities, percentage of healthy household, and more equally distributed health services as to prevent diarrhea.