Abstract
Background: Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign hormonal related fibrovascular tumor which originates from superoposterior area of sphenopalatine foramen. Purpose: To determineER-ß expression of JNA patient at Cipto Mangunkusumo Hospital. Method: Descriptive study to determine ß-estrogen receptor (ER-ß) on 27 JNA patients who had been treated at Oncology Division ENT Departement Cipto Mangunkusumo Hospital between 2001-2008 was conducted. Results: ER-ß expression of JNA in this study is 100%. Based on ER-ß staining intensity, 18.5% gave strong intensity, 29.6% with moderate intensity, and 51.9% with weak intensity. According to positive ER-ß cellular, it consist of three groups: less than 25% positive, 25-50% positive, and more than 50% positive, and the result is 3.7%, 3.7%, and 92.6% respectively. Conclusion: Immunohistochemical examination revealed 100% ER-ß expression.
Keywords: Juvenile nasopharyngeal angiofibroma (JNA), ER-ß expression
Keywords: Juvenile nasopharyngeal angiofibroma (JNA), ER-ß expression
Original language | English |
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Pages (from-to) | 8, 16 |
Journal | Oto Rhino Laryngologica Indonesiana |
Volume | 41 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2011 |