Formulation of tobacco based mosquito repellent to avoid dengue fever

Mahdi Jufri, Evita Irmayanti, Misri

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Commercial mosquito repellents containssynthetic substances such as DEET (N, Ndiethyl-3-methylbenzamide), DEPA (N, N-diethyl phenylacetamide), permethrin, and deltamethrin as active component, which can be absorbed to human body and cause some systemic poisoning. This research studiesthe potential of tobacco leaves based repellent which is not only safe for human but also environmentally friendly. Tobacco leaves was extracted using fast pyrolysis at 500°C. The condensed biooil was then made into biomass based repellent. The repellent was tested directly to human to evaluate the effects on the skin and the effectivity as a repellent. The active compounds of repellent found was nicotine, d-Limonene, indole, and pyridine. Nicotine was the highest substance from biooil at 31.1%; 16.7%; and 18.9%, respectively. Biooil was added to repellent mixture as active compound with different concentration (0%; 0.5%; 1.5%; and 3%, all in %wt). Repellent tested showed a desired result, where not only the repellent didn’t take any side effect on human skin, the effectivity of each concentration was 38.`%; 45.8%; 46.4%; and 57.1%, respectively.

Original languageEnglish
Pages (from-to)140-145
Number of pages6
JournalInternational Journal of PharmTech Research
Issue number7
Publication statusPublished - 2016


  • Biooil
  • Mosquito repellent
  • Pesticide
  • Tobacco leaves


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