TY - JOUR
T1 - Formulation of oleozon with Phaleria macrocarpa and Cinnamomum burmanii extract for diabetic wound treatment
AU - Salsabila, N.
AU - Moulydia, F.
AU - Bismo, S.
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2018/4/6
Y1 - 2018/4/6
N2 - In this work, the effect of ozonation on coconut oil and mixture of coconut oil and olive oil was studied. The properties of ozonated oils (oleozon) were analytically tested by the method of iodine number, acid number, peroxide number, and FT-IR as general chemical substances. Ozonation may increase the peroxide and acid number for both oils but decrease the iodine number. The best ozonation condition has been seen from an increase of 277.52% acid number, peroxide number about 114.77 meq O2 2-/kg oil, and decrease of iodine number up to 22%. Furthermore, ozonated oils were mixed with herbal extract and be tested the diabetic wound healing ability through antibacterial activity test. A mixture of 160 mL coconut oil that ozonated for 72 hours and 0.18 gram herbal extracts with n-hexane solvent showed the highest inhibition zone of 18.3 mm in Staphylococcus aureus bacteria.
AB - In this work, the effect of ozonation on coconut oil and mixture of coconut oil and olive oil was studied. The properties of ozonated oils (oleozon) were analytically tested by the method of iodine number, acid number, peroxide number, and FT-IR as general chemical substances. Ozonation may increase the peroxide and acid number for both oils but decrease the iodine number. The best ozonation condition has been seen from an increase of 277.52% acid number, peroxide number about 114.77 meq O2 2-/kg oil, and decrease of iodine number up to 22%. Furthermore, ozonated oils were mixed with herbal extract and be tested the diabetic wound healing ability through antibacterial activity test. A mixture of 160 mL coconut oil that ozonated for 72 hours and 0.18 gram herbal extracts with n-hexane solvent showed the highest inhibition zone of 18.3 mm in Staphylococcus aureus bacteria.
UR - http://www.scopus.com/inward/record.url?scp=85046274230&partnerID=8YFLogxK
U2 - 10.1088/1757-899X/334/1/012069
DO - 10.1088/1757-899X/334/1/012069
M3 - Conference article
AN - SCOPUS:85046274230
SN - 1757-8981
VL - 334
JO - IOP Conference Series: Materials Science and Engineering
JF - IOP Conference Series: Materials Science and Engineering
IS - 1
M1 - 012069
T2 - 3rd International Conference on Chemical Engineering Sciences and Applications 2017, ICChESA 2017
Y2 - 20 September 2017 through 21 September 2017
ER -
