Formulation of oleozon with Phaleria macrocarpa and Cinnamomum burmanii extract for diabetic wound treatment

N. Salsabila, F. Moulydia, Setijo Bismo

Research output: Contribution to journalConference articlepeer-review

1 Citation (Scopus)

Abstract

In this work, the effect of ozonation on coconut oil and mixture of coconut oil and olive oil was studied. The properties of ozonated oils (oleozon) were analytically tested by the method of iodine number, acid number, peroxide number, and FT-IR as general chemical substances. Ozonation may increase the peroxide and acid number for both oils but decrease the iodine number. The best ozonation condition has been seen from an increase of 277.52% acid number, peroxide number about 114.77 meq O2 2-/kg oil, and decrease of iodine number up to 22%. Furthermore, ozonated oils were mixed with herbal extract and be tested the diabetic wound healing ability through antibacterial activity test. A mixture of 160 mL coconut oil that ozonated for 72 hours and 0.18 gram herbal extracts with n-hexane solvent showed the highest inhibition zone of 18.3 mm in Staphylococcus aureus bacteria.

Original languageEnglish
Article number012069
JournalIOP Conference Series: Materials Science and Engineering
Volume334
Issue number1
DOIs
Publication statusPublished - 6 Apr 2018
Event3rd International Conference on Chemical Engineering Sciences and Applications 2017, ICChESA 2017 - Banda Aceh, Indonesia
Duration: 20 Sep 201721 Sep 2017

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