Formulation of microemulsion propolis fluoride (PF) as varnish topical agent to stop activity of teeth caries

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

Topical fluoride is proven to have higher efficacy in preventing dental caries with low production cost and easy to apply. The objective of this research is to formulate alternative agent topical fluoride NH4F 5% mixed with extract ethanol propolis (EEP) in the micro-emulsion system that has high stability, antimicrobial activity, and remineralization capability to arrest teeth caries activity. By using total plate count (TPC) analysis, formulation 2.7% EEP; 6,3% surfactant; and 90,9% NH4F shows good perform to inhibit cariogenic bacteria development around 78-80%. Scanning Electron Microscopy (SEM) and Energy Dispersive X-Ray (EDX) result also showed that sample successfully remineralized enamel surface. In addition, sample showed good pH, flavonoid, and polyphenol stability for 40 days.

Original languageEnglish
Title of host publicationBiomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publicationProceedings of the 1st International Symposium of Biomedical Engineering, ISBE 2016
EditorsYudan Whulanza, Sugeng Supriadi, Muhamad Sahlan, Basari
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735414853
DOIs
Publication statusPublished - 21 Feb 2017
Event1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016 - Depok City, Indonesia
Duration: 31 May 20161 Jun 2016

Publication series

NameAIP Conference Proceedings
Volume1817
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016
Country/TerritoryIndonesia
CityDepok City
Period31/05/161/06/16

Keywords

  • NHF
  • extract ethanol Propolis (EEP)
  • microemulsion
  • stability, antibacterial activity test, remineralization test

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