TY - JOUR
T1 - Formulation and characterization of rice bran oil in alginate microcapsules
AU - Nashihah, Siti
AU - Mun'im, Abdul
AU - Sutriyo, null
AU - Saputri, Fadlina Chany
N1 - Funding Information:
This study financially was supported by Hibah PITTA 2017 from Directorate of Research and Community Engagement, Universitas Indonesia.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Objective: This study was conducted to evaluate the encapsulated Rice Bran Oil with sodium alginate to improve stability and reduce rancidity by using ionic gelation method. Method: Response Surface Methodology design were used to optimized microcapsule condition. Thirteen formula of Rice Bran Oil microcapsules were prepared in differential ratio and evaluated for physical characteristic, level of γ-oryzanol content, entrapment efficiency, in vitro release of Rice Bran Oil microcapsules. Results: Between all formulas, the ratio of 40:50:10 for Rice Bran Oil, sodium alginate and emulgator respectively, had the highest entrapment efficiency and in the physical characteristic parameter.The microcapsules were in particle range of 580 and 747µm. the in vitro evaluation showed that RBO was release from microcapsules in intestinal simulated digestion (50.64%) for 8 hours. Conclusion: Rice Bran Oil, sodium alginate and emulgator with the ratio of 40:50:10 indicated establish formula to create RBO microcapsules. Key words: Formulation, Rice Bran Oil, Microcapsules, Ionic gelation, Sodium alginate.
AB - Objective: This study was conducted to evaluate the encapsulated Rice Bran Oil with sodium alginate to improve stability and reduce rancidity by using ionic gelation method. Method: Response Surface Methodology design were used to optimized microcapsule condition. Thirteen formula of Rice Bran Oil microcapsules were prepared in differential ratio and evaluated for physical characteristic, level of γ-oryzanol content, entrapment efficiency, in vitro release of Rice Bran Oil microcapsules. Results: Between all formulas, the ratio of 40:50:10 for Rice Bran Oil, sodium alginate and emulgator respectively, had the highest entrapment efficiency and in the physical characteristic parameter.The microcapsules were in particle range of 580 and 747µm. the in vitro evaluation showed that RBO was release from microcapsules in intestinal simulated digestion (50.64%) for 8 hours. Conclusion: Rice Bran Oil, sodium alginate and emulgator with the ratio of 40:50:10 indicated establish formula to create RBO microcapsules. Key words: Formulation, Rice Bran Oil, Microcapsules, Ionic gelation, Sodium alginate.
UR - http://www.scopus.com/inward/record.url?scp=85042522612&partnerID=8YFLogxK
U2 - 10.5530/jyp.2018.10.10
DO - 10.5530/jyp.2018.10.10
M3 - Article
AN - SCOPUS:85042522612
SN - 0975-1483
VL - 10
SP - 37
EP - 40
JO - Journal of Young Pharmacists
JF - Journal of Young Pharmacists
IS - 1
ER -