Fallopian tube carcinoma: A case report on its histopathological aspect

Fallopian tube carcinoma (FTC) is one of the rarest malignancies of female reproductive system, accounting for only 0.14%-1.8% of all gynecological cancers. Establishing a clear diagnosis and prognosis of FTC are generally considered difficult. In this study, we aimed to determine the histopathology of FTC and to determine the correlation between its histopathological and clinical findings. A 54-year-old unmarried woman presented with nausea, vomiting, and abdominal pain since 1 month prior to admission. She was diagnosed with suspected ovarian carcinoma with pleural effusions based on clinical and tumor marker tests and imaging. Accordingly, exploratory laparotomy was performed, and ascites and enlarged fallopian tubes that adhered to the rectosigmoid were noted. Subsequently, she underwent total hysterectomy, bilateral salpingooophorectomy, omentectomy, peritoneal biopsy, and loop sigmoid colostomy because of the adhesion. Pathological analysis revealed highgrade serous carcinoma in both fallopian tubes and ovaries. Furthermore, pleural fluid cytology showed positive results for a metastatic tumor. Thus, six cycles of docetaxel-carboplatin chemotherapy were administered. Primary FTC is a rare gynecological malignancy. Serous FTC resembles the tumors of its ovarian counterparts with papillae, cellular buds, slit-like glandular spaces, solid sheets, and occasionally tumor giant cells and psammoma bodies.