Extracranial Vertebral Artery Pulsatility Index o Ischemic Stroke Patients and Associated Comorbidities

Fadila Asmaniar, Taufik Mesiano, M. Kurniawan, Rakhmad Hidayat, Al Rasyid

Research output: Contribution to conferenceAbstract


Background: Vertebral artery (VA), the major vascularization of posterior circulation, supports the cerebral blood flow when the anterior circulation is compromised. Doppler ultrasound is a non-invasive tool for evaluating extracranial arteries in patients with cerebrovascular diseases. Pulsatility index (PI) reflects distal vascular resistance and large vessel stiffness, associated with ischemic stroke.

Aim: To describe the vertebral arteries' PI in pre-existing ischemic stroke subjects with their comorbidities.

Methods: This is a cross-sectional study from the stroke registry of Cipto Mangunkusumo General Hospital, Jakarta, Indonesia. Extracted data were within January to December 2020. Ultrasonographic parameters were Peak Systolic Volume (PSV), End Diastolic Volume (EDV), to formulate Pulsatility Index (PI). Mean difference between PI of single comorbidity group and of multimorbidity group for each VA side was compared with Mann-Whitney test.

Results: There were 71 subjects, with the majority of male (62%), with mean age 59,6±9.9. The most prevalent comorbidities were hypertension (82%), diabetes mellitus (46%), and coronary heart disease (CHD) (25%). There were 45% subjects with multimorbidity. Right VA PI (1,03 (0,85-1,35)) and left VA PI (1,00 (0,87-1,20)) were within normal limit. Our data showed no statistical difference between vertebral arteries PI of single and multimorbidity group in bilateral VAs.

Conclusion: There were no increased PI of bilateral vertebral arteries in our findings, despite pre-existing comorbidities. This might also explain vertebral arteries' patency in maintaining cerebral blood flow through posterior circulation in ischemic stroke individuals with vascular comorbidities
Original languageEnglish
Publication statusPublished - Dec 2021
EventAsia Pacific Stroke Conference 2021: Cerebrovascular Diseases - Virtual Conference, Chennai, India
Duration: 9 Dec 202111 Dec 2021


ConferenceAsia Pacific Stroke Conference 2021


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