TY - JOUR
T1 - Expression of Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Carcinoma From Cytology Specimens
AU - Rahmiati,
AU - Manurung, Evalina Panorangan
AU - Lisnawati,
AU - Handayani, Supri Irianti
PY - 2012
Y1 - 2012
N2 - Lung carcinoma is the number one cause of death from cancer. Non-Small cell lunng carcinoma (NSCLC) consist of three subtypes, namely squamous cell carcinoma (SCC), adenocarcinom, and large cell carcinoma. Epidermal Growth Factor Receptor (EGFR) is a transmembrane reeptor that plays an important role in the process of cell growth. EGFR expression in NSCLC is often different in each NSCLC subtypes. Overexpresion of EGFR protein and EGFR gene amplication can be used as predictor of tyrosine kinase inhibitor therapy to improve prognosis. EGFR protein expression assessment of cytology specimens is rarely, especially in Indonesia. The aim of this study was to evaluate the diffrences between EGFR in each subtype of NSCLC from cytological specimen.
AB - Lung carcinoma is the number one cause of death from cancer. Non-Small cell lunng carcinoma (NSCLC) consist of three subtypes, namely squamous cell carcinoma (SCC), adenocarcinom, and large cell carcinoma. Epidermal Growth Factor Receptor (EGFR) is a transmembrane reeptor that plays an important role in the process of cell growth. EGFR expression in NSCLC is often different in each NSCLC subtypes. Overexpresion of EGFR protein and EGFR gene amplication can be used as predictor of tyrosine kinase inhibitor therapy to improve prognosis. EGFR protein expression assessment of cytology specimens is rarely, especially in Indonesia. The aim of this study was to evaluate the diffrences between EGFR in each subtype of NSCLC from cytological specimen.
UR - http://ojs-mki.idionline.org/index.php/jinma/article/view/252
M3 - Article
SN - 2654-3796
JO - Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
JF - Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
ER -
