Evaluation of the potential of Nano Silver Fluoride against Streptococcus mutans and Enterobacter faecalis in various stages of biofilm maturation

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Silver Diamine Fluoride (SDF) is a liquid that has been proven to be an anti caries agent. Unfortunately, SDF leaves a black stain on the surface of the teeth where it was applicated, and it also has a metallic taste. Nano Silver Fluoride has the potential to replace Silver Diamine Fluoride as an anti caries agent without having the same side effects. To analyze the effect of NSF on the viability of Streptococcus mutans and Enterobacter faecalis in various phases of biofilm maturation compared to SDF, E. faecalis and S. mutans biofilm was incubated for 4 hours (adherence phase), 12 hours (active accumulation phase) and 24 hours (maturation phase) at 37 °C, then exposed to NSF at concentration (Ag + 0,4%+F - 2,26%), (Ag + 0,9%+F - 2,26%), (Ag + 1,4%+F - 2,26%), (Ag + 1,9%+F - 2,26%) for 1 hour. The percentage of viability was tested with MTT assay. Biofilm viability of E. faecalis and S. mutans in various phases showed no significant difference (p>0,05) in one-way ANOVA, compared to SDF. Results from this study showed that NSF was comparable with Silver Diamine Fluoride in inhibiting formation of E. faecalis and S. mutans biofilm.

Original languageEnglish
Title of host publication3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publicationProceedings of the International Symposium of Biomedical Engineering, ISBE 2018
EditorsPraswasti P.D.K. Wulan, Misri Gozan, Sotya Astutiningsih, Ghiska Ramahdita, Radon Dhelika, Prasetyanugraheni Kreshanti
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735418226
DOIs
Publication statusPublished - 9 Apr 2019
Event3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018 - Jakarta, Indonesia
Duration: 6 Aug 20188 Aug 2018

Publication series

NameAIP Conference Proceedings
Volume2092
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
CountryIndonesia
CityJakarta
Period6/08/188/08/18

Keywords

  • biofilm
  • Enterobacter faecalis
  • nano silver fluoride
  • Streptococcus mutans
  • viability

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  • Cite this

    Gultom, F. P., Khoirunnisa, N., Sahlan, M., & Soekanto, S. A. (2019). Evaluation of the potential of Nano Silver Fluoride against Streptococcus mutans and Enterobacter faecalis in various stages of biofilm maturation. In P. P. D. K. Wulan, M. Gozan, S. Astutiningsih, G. Ramahdita, R. Dhelika, & P. Kreshanti (Eds.), 3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the International Symposium of Biomedical Engineering, ISBE 2018 [030007] (AIP Conference Proceedings; Vol. 2092). American Institute of Physics Inc.. https://doi.org/10.1063/1.5096711